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members of the Federal DRI Research Synthesis Subcommittee, which supported the workshop and provided useful substantive input.

The project was sponsored by the U.S. and Canadian governments, specifically:

  • U.S. Department of Health and Human Services

    National Institutes of Health, Division of Nutrition Research Coordination

    National Institutes of Health, Office of Dietary Supplements

    Office of Disease Prevention and Health Promotion

  • U.S. Department of Agriculture, Agricultural Research Service

  • Health Canada, Food Directorate, Bureau of Nutritional Sciences

  • Canadian Institutes of Health Research, Institute of Nutrition, Metabolism and Diabetes


Two members of the workshop planning group—Drs. John W. Suttie and Susan J. Whiting—moderated the DRI Research Synthesis Workshop. After an overview and demonstration of the DRI Research Synthesis Database, panels of experts addressed DRI research recommendations related to each of the six DRI nutrient reports, the two DRI applications reports, and three cross-cutting topics: (1) setting DRIs for children, (2) Tolerable Upper Intake Levels, and (3) relevant new and underutilized research techniques. Periodically, presenters and other attendees took part in lively discussions. During the wrap-up session, moderator John Suttie and four other individuals—from U.S. and Canadian agencies, industry, and academia—provided their perspectives on the workshop.

This report is a summary of the workshop presentations and discussions. Meeting transcripts and slides used during presentations served as the basis for the summary. Topics frequently mentioned by individual participants as continuing knowledge gaps include the following:

  • Requirements of children, pregnant and lactating women, and the elderly

  • Individual variation of requirements caused by genetics and epigenetics, lifestyle, environment, and/or geography

  • The need for biomarkers that are able to predict functional outcomes and chronic diseases

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