. "6 Emerging Principles of Regulatory Evolution--BENJAMIN PRUD'HOMME, NICOLAS GOMPEL, and SEAN B. CARROLL." In the Light of Evolution: Volume 1. Adaptation and Complex Design. Washington, DC: The National Academies Press, 2007.
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In the Light of Evolution, Volume I: Adaptation and Complex Design
FIGURE 6.2 Regulatory evolution and wing pigmentation pattern diversity. A suite of transcription factors control the development of the fly wing, each one being expressed in a particular pattern. Altogether, these expression patterns constitute a wing trans-regulatory landscape, conserved among Drosophila species (Top). The recruitment of a subset of the trans-regulatory landscape components by pigmentation genes results in the corresponding redeployment of these genes (Middle) and ultimately in a novel wing pigmentation pattern (Bottom). The recruitment of different combinations of trans-acting factors in different fly species yields distinct pigmentation patterns. In Middle, rectangles with motif represent binding sites for different trans-regulatory landscape components.