formal analyses of uncertainties and for undefined “central estimates” may, in the absence of peer-reviewed technical guidance on the evaluation and expression of uncertainties, result in risk characterizations of reduced rather than enhanced quality and consistency. These are serious concerns because any attempt to advance the practice of risk assessment that does not lean heavily on nearly 25 years of expert study of the topic and reflect scientific consensus is likely to produce the opposite effect. The chapters that follow in this report provide further discussion of those concerns.

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