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Cancer Biomarkers: The Promises and Challenges of Improving Detection and Treatment (2007)

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. "Front Matter." Cancer Biomarkers: The Promises and Challenges of Improving Detection and Treatment. Washington, DC: The National Academies Press, 2007.

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Cancer Biomarkers: The Promises and Challenges of Improving Detection and Treatment

3-4

  

Examples of Standards and Guidelines for the Development and Use of Biomarkers,

  

86

3-5

  

Estrogen Receptor—The Classic Cancer Biomarker,

  

96

3-6

  

Herceptin/HercepTest Development and Approval,

  

98

3-7

  

EGFR Inhibitors—The Quest for Targeting Biomarkers,

  

102

4-1

  

Assessing the Value of OncotypeDX and MammaPrint,

  

118

FIGURE

2-1

  

EDRN informatics infrastructure,

  

44

TABLES

1-1

  

Use of Cancer Biomarkers in Patient Care,

  

23

1-2

  

Use of Biomarkers in Drug Development,

  

24

2-1

  

Examples of Biomarker Categories and High-Throughput Methods of Discovery,

  

30

2-2

  

Biomarker Validation and Qualification Requires Demonstration of Fitness for a Specified Purpose,

  

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