. "16 Mendelian Randomization: Genetic Variants as Instruments for Strengthening Causal Inference in Observational Studies--George Davey Smith and Shah Ebrahim." Biosocial Surveys. Washington, DC: The National Academies Press, 2007.
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Timpson, N.J., Lawlor, D.A., Harbord, R.M., Gaunt, T.R., Day, I.N.M., Palmer, L.J., Hattersley, A.T., Ebrahim, S., Lowe, G.D.O., Rumley, A., and Davey Smith, G. (2005). C-reactive protein and its role in metabolic syndrome: Mendelian randomization study. Lancet,366, 1954-1959.
Tybjaerg-Hansen, A., Steffensen, R., Meinertz, H., Schnohr, P., and Nordestgaard, B.G. (1998). Association of mutations in the apolipoprotein B gene with hypercholesterolemia and the risk of ischemic heart disease. New England Journal of Medicine, 338, 1577-1584.
Umbach, D.M., and Weinberg, C.R. (1997). Designing and analysing case-control studies to exploit independence of genotype and exposure. Statistics in Medicine, 16, 1731-1743.
Verma, S., Szmitko, P.E., and Ridker, P.M. (2005). C-reactive protein comes of age. NatureClinical Practice, 2, 29-36.
Wacholder, S., Rothman, N., and Caporaso, N. (2000). Population stratification in epidemiologic studies of common genetic variants and cancer: Quantification of bias. Journal ofthe National Cancer Institute, 92, 1151-1158.
Wacholder, S., Rothman, N., and Caporaso, N. (2002). Counterpoint: Bias from population stratification is not a major threat to the validity of conclusions from epidemiological studies of common polymorphisms and cancer. Cancer Epidemiology, Biomarkers andPrevention, 11, 513-520.
Waddington, C.H. (1942). Canalization of development and the inheritance of acquired characteristics. Nature, 150, 563-565.
Weiss, K., and Terwilliger, J. (2000). How many diseases does it take to map a gene with SNPs? Nature Genetics, 26, 151-157.
Willett, W.C. (1990). Vitamin A and lung cancer. Nutrition Reviews, 48, 201-211.
Willett, W.C. (2001). Eat, drink, and be healthy: The Harvard Medical School guide to healthy eating. New York: Free Press.
Williams, R.S., and Wagner, P.D. (2000). Transgenic animals in integrative biology: Approaches and interpretations of outcome. Journal of Applied Physiology, 88, 1119-1126.
Wright, A.F., Carothers, A.D., and Campbell, H. (2002). Gene-environment interactions: The BioBank UK study. Pharmacogenomics Journal, 2, 75-82.
Wolf, U. (1995). The genetic contribution to the phenotype. Human Genetics, 95, 127-148.
Wu, T., Dorn, J.P., Donahue, R.P., Sempos, C.T., and Trevisan, M. (2002). Associations of serum C-reactive protein with fasting insulin, glucose, and glycosylated hemoglobin: The Third National Health and Nutrition Examination Survey, 1988-1994. AmericanJournal of Epidemiology, 155, 65-71.