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Suggested Citation:"1 Introduction." Institute of Medicine. 2007. Nutritional Risk Assessment: Perspectives, Methods, and Data Challenges: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/11940.
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1
Introduction

Presenters: Catherine E. Woteki and Robert L. Buchanan

CONTEXT

Risk assessment methods and their applications in food and nutrition have evolved considerably over the last 20 years. Concurrently, there have been important developments in approaches to assessing data sets, in statistical techniques, and in the fields of genetics, genomics, proteomics, and metabolomics. Many of these developments provide insights into how food affects human health. Risk assessment applications now occur in areas that originally were not considered to be in the risk assessment realm. Among these are applications of risk assessment to the microbiological safety of foods and human nutrition. This workshop was designed to bring together experts from many fields to consider what has been learned about the application of risk assessment to various food-and nutrition-related problems, to discuss the strengths and challenges in using risk assessment methods to inform the setting of dietary and nutritional recommendations and other forms of decision making, and to suggest next steps for making progress in these areas.

Catherine Woteki welcomed the group on behalf of the Food Forum, one of the cosponsors of the workshop. The Food Forum is a group of representatives from government agencies and academia and scientists from the food industry that operates under the auspices of the Food and Nutrition Board of the Institute of Medicine. The Food Forum discusses food-related topics ranging from risk assessment to aspects of consumer behavior. The activities in which the Food Forum is involved provide a venue for dialogue and for exploring the dimensions of different issues, but they do not result in recommendations.

Suggested Citation:"1 Introduction." Institute of Medicine. 2007. Nutritional Risk Assessment: Perspectives, Methods, and Data Challenges: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/11940.
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Robert Buchanan described how this workshop grew out of a project undertaken as part of the Interagency Risk Assessment Consortium. This consortium is a group of 17 federal agencies and organizational units within those agencies that meet to find ways to enhance the application of risk assessment to food issues. Two years ago, the consortium recognized that work by the World Health Organization (Source: http://www.who.int/ipcs/methods/ew [accessed July 10, 2007]) and others would lead to increased interest in the application of risk assessment methods to nutritional questions. Thus, the consortium worked to help plan this workshop that was designed to provide a forum for the discussion of the potential of risk assessment approaches to inform diet- and nutrition-related recommendations and decisions. Buchanan acknowledged Laina Bush within the Office of the Assistant Secretary for Planning and Evaluation of the U.S. Department of Health and Human Services for her efforts and support.

Woteki expressed special thanks to the Interagency Risk Assessment Consortium for its instrumental role in planning the workshop. Woteki also expressed appreciation to the other cosponsors: the Food and Drug Administration; the Assistant Secretary for Planning and Evaluation of the U.S. Department of Health and Human Services; the Agricultural Research Service and the Office of Risk Assessment and Cost Benefit Analysis, both of the U.S. Department of Agriculture; and the International Life Sciences Foundation.

OBJECTIVES OF THE WORKSHOP

A major objective of the workshop was to introduce the nutrition and risk assessment communities to each other and foster their collaboration. The more specific objectives of the workshop follow:

  1. Discuss the strengths and challenges of using various risk assessment approaches to inform dietary and nutritional recommendations.

  2. Explore the use of risk assessment approaches to evaluate standards for nutrient intake and the relationship of diet and nutrition to chronic disease risk.

  3. Identify next steps necessary to make progress in these areas.

Suggested Citation:"1 Introduction." Institute of Medicine. 2007. Nutritional Risk Assessment: Perspectives, Methods, and Data Challenges: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/11940.
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Page 5
Suggested Citation:"1 Introduction." Institute of Medicine. 2007. Nutritional Risk Assessment: Perspectives, Methods, and Data Challenges: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/11940.
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Page 6
Next: 2 Risk Assessment and Nutrition: Sharing Perspectives »
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For more than two decades, the practice of risk assessment has been applied to human public health issues, and policy makers have used the results of risk assessments in their decision-making process. Approaches for risk assessment have been developed for nonnutrients such as drugs, food additives, and pesticides, but approaches for risk assessment have received less attention in the nutrition area. Some aspects of the risk assessment approach used for nonnutrients are applicable to the assessment of risks related to nutrition. The overall approach, however, must be adapted and modified to take into account the unique aspects of nutrients, including the fact that both high and low nutrient intakes are associated with risk. Experience with the application of a risk assessment process to the setting of upper levels of intake for essential nutrients, for example, has uncovered a number of challenges. Adapting and developing risk assessment strategies for application in nutrition science could lead to improved approaches to the development of dietary and nutritional recommendations and thus is a topic of considerable interest.

One nonscientific but overall challenge to nutritional risk assessment relates to increasing and improving communication among experts from key disciplines in ways that could inform the nutritional risk assessment process. Among these key disciplines are nutrition, toxicology, dietary exposure assessment, economics, risk analysis, and epidemiology. How can the perspectives and methods of these diverse fields be brought together to develop more effective approaches for quantitative nutritional risk assessment? How can they be applied to a spectrum of topics related to food and nutrition—micronutrients, macronutrients, dietary supplements, whole foods, food groups, and dietary patterns? How can they help overcome the data challenges that confront nutritional risk assessors?

As a step toward improving the communication and sharing methods and information across disciplines, members of the Interagency Risk Assessment Consortium, the U.S. Health and Human Services Office of the Assistant Secretary for Planning and Evaluation, the Institute of Medicine's Food Forum, and the International Life Sciences Institute planned the Nutritional Risk Assessment Workshop. The workshop was held on February 28 and March 1, 2007, in Washington, D.C. This workshop, which was envisioned as one in a series, focused on opening a dialogue to explore the unique questions and challenges faced by nutritionists and the potential use of risk assessment methodologies to answer them. Nutritional Risk Assessment : Perspectives, Methods, and Data Challenges, Workshop Summary summarizes the happenings of this workshop.

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