TABLE 2-1 Number of Citations, by Source

Source

Number of Citations

MEDLINE

1554

EMBASE

578

PsycINFO

334

Cochrane Database of Systematic Reviews

11

Cochrane Controlled Trials Register

28

NTIS

151

Social service abstracts

97

DARE

18

Total

2771

BOX 2-1

Inclusion Criteria for Review

  • Randomized controlled trial (RCT; randomized comparative trials were only used if RCTs for a given modality demonstrated efficacy )

  • PTSD diagnosis based on DSM criteria

  • Published between 1980 and June 2007

  • Adults ages 18 and older

  • PTSD outcome measure included (primary or secondary measure)

  • English language

This review also included only primary research and no reanalyses of prior research.3

The committee was charged to “report on the highest levels of evidence available.” Although the number of studies for some treatment modalities was small, in most cases randomized controlled trials were available for review. (For clarity, it should be noted that in the psychotherapy studies, the control was not placebo, but wait list, usual care, or a type of active control.) Therefore, per part II.B of the Statement of Task, only level-I studies (RCTs) were included in the committee’s review. The committee recognizes that study designs other than RCTs can be informative for questions of effectiveness and other outcomes, but did not believe that non-RCTs would inform the core question of treatment efficacy. The committee judged

3

When there was more than one primary study based on the same data, the study with the most complete data set was used.



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