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Advancing Nuclear Medicine through Innovation
Appendix C
Commercially Available Radiopharmaceuticals
Radiopharmaceutical
Trade Name
Primary Uses
Carbon-14 Urea
Pytest
Detection of H Pylori
Cobalt-57 cyanocobalamin
Rubratope
Schilling test
Chromium-51 sodium chromate
Chromitope (Bracco)
Mallinckrodt Cr-51
Labeling red blood cells (RBC)
Fluorine-18-FDG
Positron emission tomography (PET) imaging
Gallium-67
Neoscan (GE)
DuPont Ga-67
Mallinckrodt Ga-67
Soft-tissue tumor and inflammatory process imaging
Indium-111 chloride
Indiclor (Nycomed)
Mallinckrodt In-111Cl
Labeling monoclonal antibodies and peptides (OncoScint & Octreoscan)
Indium-111 pentetate (DTPA)
Indium DTPA In-111
Imaging of cerebrospinal fluid kinetics
Indium-111 oxyquinoline (oxine)
Indium-111 oxine
Labeling leukocytes and platelets
Indium-111 Capromab pendetide
ProstaScint
Monoclonal antibody for imaging prostate cancer
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Advancing Nuclear Medicine through Innovation
Radiopharmaceutical
Trade Name
Primary Uses
Indium-111 pentetreotide
Octreoscan
Imaging neuroendocrine tumors
I-123 sodium iodide
Mallinckrodt
Amersham
Thyroid imaging and uptake
I-125 iothalamate
Glofil
Measurement of glomerular filtration
I-125 human serum albumin (RISA)
Isojex
Plasma volume determinations
I-131sodium iodide
Iodotope (Bracco)
CIS - I-131
Mallinckrodt I-131Soln
Mallinckrodt I-131 Therapy Caps
Mallinckrodt I-131 Diagnostic Caps
Thyroid uptake, imaging, and therapy
Tositumomab & Iodine I-131 Tositumomab
Bexxar
Treatment of non-Hodgkin’s lymphoma
I-131 iodomethylnorcholesterol (NP-59)
(University of Michigan)
Adrenal imaging
I-131 metaiodobenzylguanidine (MIBG)
I-131 MIBG
Imaging pheochromocytomas and neuroblastomas
P-32 chromic phosphate
Phosphocol P32
Therapy for intracavitary malignancies
P-32 sodium phosphate
Therapy for polycythemia vera
Rubidium-82 (from Sr-82/Rb-82 generator)
Cardio-Gen-82
PET imaging
Samarium-153 Lexidronam (Sm-153 EDTMP)
Quadramet
Palliative treatment of bone pain of skeletal metastases
Strontium-89
Metastron
Palliative treatment of bone pain of skeletal metastases
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Advancing Nuclear Medicine through Innovation
Radiopharmaceutical
Trade Name
Primary Uses
Tc-99m pertechnetate Generators
DuPont
Mallinckrodt DTE
Mallinckrodt FM
Amersham
Imaging thyroid, salivary glands, ectopic gastric mucosa, parathyroid glands, dacryocystography, cystography
Tc-99m Apcitide
AcuTect
Peptide imaging of deep vein thrombosis
Tc-99m bicisate (ECD)
Neurolite
Cerebral perfusion imaging
Tc-99m disofenin (DISIDA)
Hepatolite-CIS
Hepatobiliary imaging
Tc-99m exametazine (HMPAO)
Ceretec
Cerebral perfusion imaging
Tc-99m Gluceptate
Draximage
Mallinckrodt
Renal imaging
Tc-99m human serum albumin (HSA)
Imaging cardiac chambers
Tc-99m macroaggregated albumin (MAA)
Pulmolite - CIS
Macrotec (Bracco)
Technescan MAA (Mallinckrodt)
Draximage
Amersham MAA
Pulmonary perfusion
Tc-99m Mebrofenin
Choletec
Hepatobiliary imaging
Tc-99m Medronate (MDP)
Bracco
Osteolite - CIS
Draximage
Mallinckrodt
Amersham
Bone imaging
Tc-99m Mertiatide
Technescan MAG3
Renal imaging
Tc-99m Oxidronate (HDP)
Mallinckrodt HDP
Bone imaging
Tc-99m Pentetate (DTPA)
Techneplex (Bracco)
CIS-AN DTPA
CIS-DTPA
Draximage DTPA
Mallinckrodt DTPA
Nycomed DTPA
Renal imaging and function studies; Radioaerosol ventilation imaging
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Advancing Nuclear Medicine through Innovation
Radiopharmaceutical
Trade Name
Primary Uses
Tc-99m Pyrophosphate (PYP)
Phosphotec (Bracco)
Pyrolite-CIS
Pyro-CIS
Technescan PYP
Amersham PYP
Avid infarct imaging; in vivo RBC labeling
Tc-99m red blood cells
Ultratag
Imaging gastrointestinal (GI) bleeds, cardiac chambers
Tc-99m Sestamibi
Cardiolite
Miraluma
Myocardial perfusion imaging
Breast tumor imaging
Tc-99m Succimer (DMSA)
Amersham DMSA
Renal imaging
Tc-99m Sulfur Colloid (SC)
CIS-Sulfur Colloid
Nycomed - SC
Imaging liver/spleen, gastric emptying, GI bleeds
Tc-99m Tetrofosmin
Myoview
Myocardial perfusion imaging
Thallium-201
DuPont
Mallinckrodt
Amersham
Myocardial perfusion imaging; Parathyroid and tumor imaging
Y-90 Ibitumomab Tiuxetan
Zevalin
non-Hodgkin’s lymphoma
Xenon-133
DuPont Xenon
Mallinckrodt Xenon
Amersham Xenon
Pulmonary ventilation imaging
Interventional Agents
Trade Name
Use in nuclear medicine
ACD solution (anticoagulant acid Acitrate dextrose)
ACD Solution Modified
Anticoagulant used in blood labeling
Adenosine
Adenoscan
Pharmacologic stress
Ascorbic acid
Ascorbic acid
RBC labeling and HDP preparation
I.V. Dipyridamole
I.V. Persantine
Pharmacologic stress
Sincalide
Kinevac
Gallbladder ejection fraction studies
SOURCE: University of Arkansas for Medical Sciences (http://nuclearpharmacy.uams.edu/resources/PackageInserts.asp).
Representative terms from entire chapter:
name primary