Appendix F
Research Projects Supported under the Cooperative Biological Research Program (1999-present)

 

Title

Budget

Investigators

Former Soviet Union institute/ location

Russia: Active Projects

 

 

 

 

ISTC #1638

Combinatorial Antibody Libraries to Orthopoxviruses

$118,646.00

Alexander Ilyichev

State Research Center for Virology and Biotechnology (Vector), Koltsovo

ISTC #1987

Conservation of Genetic Material and Study of Genomic Structure of Different Variola Virus Strains

$668,456.00

Sergei Shchelkunov

State Research Center for Virology and Biotechnology (Vector), Koltsovo

ISTC #1989

Search for Antivirals for Treating and Prevention of Orthopoxviral Infections Including Smallpox

$716,687.00

Evgeny Belanov

State Research Center for Virology and Biotechnology (Vector), Koltsovo

ISTC #2129

Magnetometric Immunosensor for Multi-pathogen Continuous Monitoring

$496,906

Peter Sveshnikov

Research Center of Molecular Diagnostics and Therapy, Moscow

Total

 

$2,000,695.00

 

 

Russia: Completed Projects

 

 

 

 

ISTC #884

Genome of Monkeypox virus

$362,880

Sergei Shchelkunov

State Research Center for Virology and Biotechnology (Vector), Koltsovo

ISTC #919

Investigation of the immunological effectiveness of delivery in vivo of the Brucella main outer membrane protein by the Anthrax Toxin components

$108,016.00

Anatoly Noskov

State Research Center for Applied Microbiology, Obolensk



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The Biological Threat Reduction Program of the Department of Defense|From Foreign Assistance to Sustainable Partnerships Appendix F Research Projects Supported under the Cooperative Biological Research Program (1999-present)   Title Budget Investigators Former Soviet Union institute/ location Russia: Active Projects         ISTC #1638 Combinatorial Antibody Libraries to Orthopoxviruses $118,646.00 Alexander Ilyichev State Research Center for Virology and Biotechnology (Vector), Koltsovo ISTC #1987 Conservation of Genetic Material and Study of Genomic Structure of Different Variola Virus Strains $668,456.00 Sergei Shchelkunov State Research Center for Virology and Biotechnology (Vector), Koltsovo ISTC #1989 Search for Antivirals for Treating and Prevention of Orthopoxviral Infections Including Smallpox $716,687.00 Evgeny Belanov State Research Center for Virology and Biotechnology (Vector), Koltsovo ISTC #2129 Magnetometric Immunosensor for Multi-pathogen Continuous Monitoring $496,906 Peter Sveshnikov Research Center of Molecular Diagnostics and Therapy, Moscow Total   $2,000,695.00     Russia: Completed Projects         ISTC #884 Genome of Monkeypox virus $362,880 Sergei Shchelkunov State Research Center for Virology and Biotechnology (Vector), Koltsovo ISTC #919 Investigation of the immunological effectiveness of delivery in vivo of the Brucella main outer membrane protein by the Anthrax Toxin components $108,016.00 Anatoly Noskov State Research Center for Applied Microbiology, Obolensk

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The Biological Threat Reduction Program of the Department of Defense|From Foreign Assistance to Sustainable Partnerships ISTC #1176 Development of Methods for Therapy of Chronic Melioidosis with Burkholderia Specific Immunogens $1,059,785.00 Igor Kalachev State Research Center for Applied Microbiology, Obolensk ISTC #1197 Study of the Role of Yersinia pestis Lipopolysaccharides (LPS) Structural Organization in the Development of Immune Preparations $943,408.00 Andrei Anisimov State Research Center for Applied Microbiology, Obolensk ISTC #1198 Experimental Study of Antiviral Activity of Glycyrrhyzic Acid Derivatives against Marburg and Ebola Viruses $525,365.00 Andrey Pokrovsky State Research Center for Virology and Biotechnology (Vector), Koltsovo ISTC #1487 A Sampler for the Detection and Express Identification of Airborne Microorganisms $680,000.00 Alexander Tolchinsky Research Center for Toxicology and Hygienic Regulations of Biopreparations, Serpukhov ISTC #1215 Monitoring of Anthrax Infection $455,000 Nikolai Staritsyn State Research Center for Applied Microbiology, Obolensk ISTC #1233 Development of Immunofiltration and Immunoenzyme Express Diagnostic Test-Kits for the Determination of Infectious Diseases $972,354.00 Peter Sveshnikov Research Center of Molecular Diagnostics and Therapy, Moscow ISTC #1291 Study of the Genomic Structure of Crimean-Congo Hemorrhagic Fever Virus Isolates Circulating in the Southern Regions of NIS Countries $604,645.00 Vladimir Petrov State Research Center for Virology and Biotechnology (Vector), Koltsovo ISTC #1515 Development of Liposomal Forms of Specific Immunoglobulins A for Urgent Prophylaxis and Treatment of Highly Dangerous Infections $678,251.00 Alexander Ischenko State Research Institute of Highly Pure Biopreparations, St. Petersburg

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The Biological Threat Reduction Program of the Department of Defense|From Foreign Assistance to Sustainable Partnerships ISTC #1813 Design of Experimental Aerosol DNA-Vaccine Preparation against Hantaviral Infection $599,000.00 Felix Filatov Research Center for Toxicology and Hygienic Regulations of Biopreparations, Serpukhov     $6,988,704.00         $8,989,399.00     Non-Russia         Georgia: Active Projects         GG-1 Ecology, Genetic Clustering, and Virulence of Yersinia Pestis Strains Isolated for Natural Foci of Plague in Georgia $850,796.00 Lela Bakanidze National Center for Disease Control, Tbilisi GG-13 Isolation, Distribution, and Biodiversity of Selected Bibrios and Their Bacteriophages from Aquatic Environments in Georgia $673,614.00 Marina Tediashvili Eliava Institute for Bacteriophage, Microbiology and Virology, Tbilisi Georgia: Projects Under Development         GG-17 Clinical, Epidemiologic and Laboratory Based Assessment of Brucellosis in Georgia $750,000 Marine Nikolaishvili Laboratory of the Ministry of Agriculture, Tbilisi; National Center for Disease Control, Tbilisi GG-18 Active Surveillance of Especially Dangerous Pathogens in the Southern Caucuses Region $750,000 Lela Bakanidze National Center for Disease Control, Tbilisi     $3,024,410     Kazakhstan: Active Projects         KZ-1 Ecological and Socio-Economic Factors of Anthrax Foci Activity and Improvement of its Diagnosis and Prophylaxis in Kazakhstan $599,556.40 Alim Aikimbayev Kazakh Scientific Center for Quarantine and Zoonotic Diseases, Almaty

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The Biological Threat Reduction Program of the Department of Defense|From Foreign Assistance to Sustainable Partnerships KZ-2 Ecology of Brucella biotypes within Southern Kazakhstan $1,500,900.00 Stanislav Kazakov Republic Sanitary Epidemiological Station, Almaty KZ-4 Epidemiology of Crimean-Congo Hemorrhagic Fever and Hemorrhagic Fever with Renal Syndrome in the Republic of Kazakhstan $618,917.28 Bolat Ospanov Kazakh Scientific Center for Quarantine and Zoonotic Diseases, Almaty Kazakhstan: Projects Approved         KZ-16 Research on a New Highly Immunogenic Strain from Francisella Tularensis, Subspecies Mediaasiatica, a Candidate for Human Vaccine $550,000.00 Alim Aikimbayev Kazakh Scientific Center for Quarantine and Zoonotic Diseases, Almaty KZ-27 Epizootological Monitoring and Biological Characterization of the Avian Influenza Virus $1,084,000 Zhailaubay Kydyrbayev The Republic National Governmental Enterprise “Research Institute for Biological Safety Problems” Otar Kazakhstan: Projects Under Development         KZ-28 Genetic Peculiarities of Strains of Especially Dangerous Zoonotic Pathogens $750,000 Tleuli I. Tugambaev M. Aikimbaev’s Kazakh Science Center for Quarantine and Zoonotic Diseases, Almaty; National Center of Monitoring, Reference, Laboratory Diagnosing and Methodology in Veterinary Medicine, Astana     $4,019,374     Uzbekistan: Active Projects         UZ-1 Epizootological, Epidemiological Monitoring in the Republic of Uzbekistan $1,278,143.02 Aminjon Nematov Uzbek Center for Prevention and Quarantine of the Most Hazardous Infections, Tashkent UZ-2 Viral Diagnostics in Uzbekistan $951,221.03 Saida Alakbarova Institute of Virology, Tashkent

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The Biological Threat Reduction Program of the Department of Defense|From Foreign Assistance to Sustainable Partnerships UZ-4 Epidemiological Surveillance of Human and Animal Brucellosis in the Republic of Uzbekistan $786,082.88 Ulugbek Imomaliev Republican Institute of Epidemiology, Microbiology and Infectious Diseases, Tashkent Uzbekistan: Approved         UZ-10 Ecological and Virological Study of Arbovirus Infections in the South Aral Region of Uzbekistan $805,118.00 Nematullo Komilov Research Institute of Virology, Ministry of Health, Republic of Uzbekistan, Tashkent Uzbekistan: Projects Under Development         UZ-VOZ A Comprehensive Epizootological Study of Vozrozhdenie Island in the Aral Sea $600,000.00 Aminjon Nematov Uzbek Center for Prevention and Quarantine of the Most Hazardous Infections, Tashkent     $4,420,564.93     Azerbaijan: Active Projects         AJ-1         Azerbaijan: Projects Under Development         AJ-2 Clinical, Epidemiologic, and Laboratory Based Assessment of Brucellosis in Azerbaijan $750,000 Shair Gurbanov Republican Antiplague Station, Baku AJ-3 Mapping Especially Dangerous Pathogens in Azerbaijan $150,000 Faig H. Mamedzadeh Republican Antiplague Station, Baku Total Azerbaijan:   $900,000     Total Non-Russia:   $12,364,348.61     CBR Program Grand Total:   $21,353,747.61    

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