DePuy Spine (a Johnson & Johnson company):

Symphony II Platelet Concentrate System info:

Symphony II Platelet Concentrate System product insert:

Harvest Technologies LLC:

SmartPReP Platelet Concentrate System:

Medtronic Inc.:

Magellan Autologous Platelet Separator:

Payer Coverage Policies:

Three payer coverage policies were located that refer to the use of PRP in bone healing. All policies consider its use experimental and investigational or unproven for bone healing and other orthopedic indications.


CIGNA HealthCare:

Regence Group:

Online Articles:

Percutaneous injection of autogenous growth factors in patient with nonunion of the humerus. A case report (Bielecki and Gazdzik, 2006), Journal of Orthopaedics: http:Ilwww.jortho.org1200613131e15/index.htm

Treatment of recalcitrant enthesopathy of the hip with platelet rich plasma — a report of three cases (Scioli M, 2006), Clinical Orthopaedic Society News (NOTE: Article is on pages 6-7): http://www.bmetbiologics.corn/international/print/Scioli_newsletter_submission.pdf

Overview of bone grafting (2002), Medscape Today:

A comprehensive search of the Internet did not return any information regarding evidence-based practice guidelines or ongoing clinical trials for PRP for bone healing and fusion.

Search Results with Abstracts

January 15, 2007


Search terms: platelet concentrate, platelet-rich plasma combined with spinal, fusion, bone AND fusion, bone healing, orthopedic surgery, platelet concentrate, platelet gel combined with orthopedic surgery, bone healing, spinal fusion

Search limits: English-language human clinical trials and review articles published in the last 5 years

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