-
Antihistamines and oral decongestants to treat otitis media with effusion
-
Autologous bone marrow transplant with high-dose chemotherapy for advanced breast cancer
-
Chelation therapy to prevent or reverse atherosclerosis
-
Diethylstilbestrol (DES) to prevent miscarriage
-
Electronic fetal monitoring during labor without access to fetal scalp sampling
-
Episiotomy (routine) for birth
-
Extracranial-intracranial bypass to reduce the risk of ischemic stroke
-
Fenfluramine plus phentermine to treat obesity
-
Gastric bubble for morbid obesity
-
Gastric freezing for peptic ulcer disease
-
Home uterine activity monitoring to prevent preterm birth
-
Hydralazine for chronic heart failure
-
Lidocaine to prevent arrhythmia and sudden death in acute myocardial infarction
-
Mammary artery ligation for coronary artery disease
-
Optic nerve decompression surgery for nonarteritic anterior ischemic optic neuropathy
-
Quinidine for suppressing recurrences of atrial fibrillation
-
Radiation therapy for acne
-
Spinal manipulation to treat migraine or cluster headaches
-
Subcutaneous interferon alfa-2a to treat age-related macular degeneration
-
Supplemental oxygen for healthy premature babies
-
Thalidomide for sedation in pregnant women
-
Traction to treat low back pain
-
Triparanol (MER-29) for cholesterol reduction
NOTE: Adapted from Goodman (2004).
SOURCES: AHCPR (1990, 1993); BMJ (2004a,b,c); Coplen et al. (1990); Enkin et al. (1995); Feeny et al. (1986); Fletcher and Colditz (2002); Grimes (1993); The Ischemic Optic Neuropathy Decompression Trial Research Group (1995); Mello and Brennan (2001); Passamani (1991); Rossouw et al. (2002).
