Appendix Biographical Information on the Committee on Combined Exposures to Hydrogen Cyanide and Carbon Monoxide in Army Operations

William E. Halperin is professor and chairman of the Department of Preventive Medicine and Community Health at the UMDNJ New Jersey Medical School. He received his M.D., M.P.H., and Dr.P.H. from Harvard University. Previously, Dr. Halperin was deputy director of the National Institute for Occupational Safety and Health. His research interests are in occupational medicine, occupational epidemiology, and public health surveillance. Dr. Halperin was a member of the NRC Committee on Risk Assessment Methodology, and served as a member of the Committee on Toxicology’s Subcommittee on Spacecraft Water Exposure Guidelines, Subcommittee on Ethylene Oxide, and Subcommittee on Jet Fuels, Panel on Emergency Exposure Guidance Levels. He also served as a member of the IOM Committee to Survey the Health Effects of Mustard Gas and Lewisite. Dr Halperin is certified by the American Board of Preventive Medicine and the American Board of Occupational Medicine. He is currently the chair of the NRC Committee on Toxicology.


Gary P. Carlson is professor of toxicology and associate head of the School of Health Sciences at Purdue University. He received his Ph.D. in pharmacology from the University of Chicago. He was chairman of the NRC Subcommittee on Toxicologic Assessment of Low-Level Exposures to Chemical Warfare Agents. He is currently serving on the NRC’s Committee on Toxicology. He is chairman of the Society of Toxicology’s Board on Publications, and previously served as chairman of its Education Committee. Dr. Carlson is currently the secretary of the Society of Toxicology. He has served on EPA’s Joint Advisory Board/Science Advisory Panel Committees on (1) Cholinesterase Inhibition and (2) Cholinesterase and Aldicarb and on the EPA Science Advisory Board’s Panel on Drinking Water. Dr. Carlson has also served on the board of scientific counselors of the National Toxicology Program (NTP), and as chair of the NTP Technical Reports Review Committee. He is an associate editor of the Journal of Toxicology and Environmental Health and serves on the editorial board of the Journal of Toxicology.


Ronald F. Coburn is professor of physiology at the University of Pennsylvania. He received his M.D. from North Western University in 1957. He has done extensive research on carbon monoxide. He was the chairman of the Panel on Carbon Monoxide from 1972-1975. He received the N.I.H. merit award in 1997. He previously served on the NRC Committee on Medical and Biological Effects of Air Pollutants (1972-1976). Dr. Coburn is on the editorial boards of American Journal of Physiology, Journal of Applied Physiology, Pulmonary Pharmacology, and Lung.


James E. Dennison is a Certified Industrial Hygienist and owner of Century Environmental Hygiene LLC, Fort Collins, CO. Dr. Dennison received his Ph.D. in Environmental Health Toxicology from Colorado State University. His doctoral thesis involved physiologically-based pharmacokinetic modeling (PBPK) of complex mixtures of gasoline in rats. He has worked with the National Advisory Committee on Acute Exposure Guideline Levels (AEGLs) committee performing PBPK modeling of CNS



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Appendix Biographical Information on the Committee on Combined Exposures to Hydrogen Cyanide and Carbon Monoxide in Army Operations William E. Halperin is professor and chairman of the Department of Preventive Medicine and Community Health at the UMDNJ New Jersey Medical School. He received his M.D., M.P.H., and Dr.P.H. from Harvard University. Previously, Dr. Halperin was deputy director of the National Institute for Occupational Safety and Health. His research interests are in occupational medicine, occupational epidemiology, and public health surveillance. Dr. Halperin was a member of the NRC Committee on Risk Assessment Methodology, and served as a member of the Committee on Toxicology’s Subcommittee on Spacecraft Water Exposure Guidelines, Subcommittee on Ethylene Oxide, and Subcommittee on Jet Fuels, Panel on Emergency Exposure Guidance Levels. He also served as a member of the IOM Committee to Survey the Health Effects of Mustard Gas and Lewisite. Dr Halperin is certified by the American Board of Preventive Medicine and the American Board of Occupational Medicine. He is currently the chair of the NRC Committee on Toxicology. Gary P. Carlson is professor of toxicology and associate head of the School of Health Sciences at Purdue University. He received his Ph.D. in pharmacology from the University of Chicago. He was chairman of the NRC Subcommittee on Toxicologic Assessment of Low-Level Exposures to Chemical Warfare Agents. He is currently serving on the NRC’s Committee on Toxicology. He is chairman of the Society of Toxicology’s Board on Publications, and previously served as chairman of its Education Committee. Dr. Carlson is currently the secretary of the Society of Toxicology. He has served on EPA’s Joint Advisory Board/Science Advisory Panel Committees on (1) Cholinesterase Inhibition and (2) Cholinesterase and Aldicarb and on the EPA Science Advisory Board’s Panel on Drinking Water. Dr. Carlson has also served on the board of scientific counselors of the National Toxicology Program (NTP), and as chair of the NTP Technical Reports Review Committee. He is an associate editor of the Journal of Toxicology and Environmental Health and serves on the editorial board of the Journal of Toxicology. Ronald F. Coburn is professor of physiology at the University of Pennsylvania. He received his M.D. from North Western University in 1957. He has done extensive research on carbon monoxide. He was the chairman of the Panel on Carbon Monoxide from 1972-1975. He received the N.I.H. merit award in 1997. He previously served on the NRC Committee on Medical and Biological Effects of Air Pollutants (1972- 1976). Dr. Coburn is on the editorial boards of American Journal of Physiology, Journal of Applied Physiology, Pulmonary Pharmacology, and Lung. James E. Dennison is a Certified Industrial Hygienist and owner of Century Environmental Hygiene LLC, Fort Collins, CO. Dr. Dennison received his Ph.D. in Environmental Health Toxicology from Colorado State University. His doctoral thesis involved physiologically-based pharmacokinetic modeling (PBPK) of complex mixtures of gasoline in rats. He has worked with the National Advisory Committee on Acute Exposure Guideline Levels (AEGLs) committee performing PBPK modeling of CNS 23

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Combined Exposures to Hydrogen Cyanide and Carbon Monoxide in Army Operations depressants to help establish AEGL values for several chemicals. He performs consulting work as a Certified Industrial Hygienist providing advice on testing, evaluation, and control of chemical agents such as heavy metals, solvents, pesticides, and biological materials. He currently serves as the vice chair of the Biological Monitoring Committee of the American Industrial Hygiene Association. Jeffrey W. Fisher is a Professor in the Department of Environmental Health Science, College of Public Health at the University of Georgia (UGA). He joined the University of Georgia in 2000 and served as Department Head of the Department of Environmental Health Science from 2000 to 2006. He now serves as Director of the Interdisciplinary Toxicology Program at UGA. He spent most of his career at the Toxicology Laboratory, Wright Patterson AFB, where he was Principal Investigator and Senior Scientist in the Toxics Hazards Division and Technical Advisor for the Operational Toxicology Branch. Dr. Fisher research interests are in the development and application of biologically based mathematical models to ascertain health risks from environmental and occupational chemical exposures. Dr. Fisher’s modeling experience includes working with chlorinated and non-chlorinated solvents, fuels, PCB, pyrethroids and perchlorate. Dr. Fisher has published over 100 papers on pharmacokinetics and PBPK modeling in laboratory animals and humans. He has served on several panels and advisory boards for the DoD, ATSDR, USEPA and non-profit organizations. He is a member of the National Academy of Sciences subcommittee on Acute Exposure Guideline Levels (2004-present) and is a Fellow of the Academy of Toxicological Sciences. James J. McGrath is professor emeritus at Texas Tech University Health Sciences Center, Lubbock, TX. He received his Ph.D. from Indiana University in 1968. Dr. McGrath served at EPA’s Office of Risk Assessment and was awarded a Silver Star in recognition of work in evaluating the world’s health and toxicology literature for relevancy to standard setting for diesel exhausts and worked on Air Quality Criteria for Carbon Monoxide, and also served as a consultant for Indoor Air Quality for the EPA’s new campus. He served as a principal author for the EPA’s Air Quality Criteria for Particulate Matter for several chapters. He is serving (or has served) on the editorial boards of American Journal of Physiology, Science, Molecular Pharmacology, Journal of Applied Toxicology, Journal of Toxicology and Environmental Health, Toxicology Letters, and CRC Press. He has served on the Society of Toxicology’s Inhalation Toxicology specialty section. Chiu-Wing Lam is a senior toxicologist at Wyle Laboratories in Houston, TX. He received his Ph.D. in toxicology from the University of Rochester in 1983. He is a diplomate of the American Board of Toxicology. He has drafted numerous toxicological risk assessment documents on spacecraft maximum allowable concentrations (SMACs) since 1990. The SMAC values (for time durations ranging from 1 hr to 180 days) are valuable guidelines to NASA for their space station and space shuttle documents. He also drafted the hydrogen cyanide SMAC document. Dr. Lam has conducted numerous toxicological assessments of payload and utility chemicals used in Space Shuttle and Space Station, providing consultations to NASA flight surgeons, safety engineers, and payload customers on toxicological issues. George C. Rodgers is professor of pediatrics at the University of Louisville, Kentucky. He received his Ph.D. in 1964 from Yale University and received his M.D. in 1975 from the State University of New York, Syracuse. He is board certified in pediatrics and medical technology. He is a member of the National Advisory Committee on Acute Exposure Guideline Levels; he was the chemical manager for the carbon monoxide AEGLs document that was reviewed by the NRC. He also served on the American Society of Safety Engineers, Z390: Accredited Standards Committee on Hydrogen Sulfide Safety Training. He is a fellow of the American College of Medical Toxicology. He is on the editorial board of Poisindex. He was a member of the Firefigthers Safety Act Technical Committee. He was president of the American Association of Poison Control Centers. He has served on committees of governmental agencies, such as EPA, ATSDR, and CDC. 24

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Appendix Sylvia Talmage is a senior toxicologist at Summitec Corporation, a contractor for Oak Ridge National Laboratory. She received her Ph.D. from the University of Tennessee. She is a diplomate of the American College of Toxicology. She served on the NRC Subcommittee for the Review of the Risk Assessment of Methyl Bromide. She previously served for 26 years at Oak Ridge National Laboratory, where she performed numerous toxicological risk assessments for hazardous chemicals. She is the author of numerous acute exposure guideline level (AEGL) documents that were reviewed by the NRC. She also drafted the hydrogen cyanide AEGL document. She has also provided advice to EPA and the U.S. Army on matters related to toxicology and risk assessment. 25

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