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Appendix B Acronyms AIDS acquired immunodeficiency syndrome ANRS Agence Nationale de Recherche sur le Sida (France) ANVISA Brazilian National Health Vigilance Agency ART antiretroviral therapy AVAC AIDS Vaccine Advocacy Coalition CAPRISA Centre for the AIDS Program of Research in South Africa CDC Centers for Disease Control and Prevention (U.S.) CMED Medicines Market Regulation Chamber DMC Data Monitoring Committee DSMB Data Safety Monitoring Board EIA enzyme immunoassay ELISA Enzyme-Linked ImmunoSorbent Assay EMEA European Agency for the Evaluation of Medicinal Products FDA Food and Drug Administration (U.S.) FHI Family Health International HIV human immunodeficiency virus HPTN HIV Prevention Trials Network HSV herpes simplex virus HVTN HIV Vaccine Trials Network IAVI International AIDS Vaccine Initiative IND Investigational New Drug application (to FDA, U.S.) IOM Institute of Medicine (U.S.) IPM International Partnership for Microbicides ITT intent-to-treat analysis MCC Medicines Control Council (South Africa) 234
APPENDIX B 235 MDP Microbicides Development Programme MRC Medical Research Council MTN Microbicide Trial Network NIAID National Institute of Allergy and Infectious Diseases (U.S.) NIH National Institutes of Health (U.S.) PEP post-exposure prophylaxis PI principal investigator PrEP pre-exposure prophylaxis STD sexually transmitted disease STI sexually transmitted infection TDF tenofovir disoproxil fumarate UNAIDS The Joint United Nations Programme on HIV/AIDS USAID U.S. Agency for International Development WHO World Health Organization