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Herpes simplex viruses 1 & 2

Glycoprotein produced by recombinant DNA technology

Children up to age 12 and older susceptibles

3,788,337

4

15

10

25

378,833,700

379

 

Attenuated live virus

 

3,788,337

1

15

10

25

94,708,425

95

Herpesvirus varicellae

Attenuated live virus

Recipients of bone marrow and organ transplants and persons under age 25 with leukemias or lymphoms

12,757

2

25

10

35

892,990

0.9

 

 

Normal susceptibles, routine for children (booster for adults)

3,788,337

2

18.75

10

28.75

217,829,378

218

Influenza viruses A & B

Subunit vaccine (purified hemagglutinin/neuraminidase proteins)

High-risk population as currently defined (see Appendix K)

48,000,00

a

a

a

 

200,160,000

200

 

Attenuated live virus

High-risk population as currently defined

48,00,000

a

a

a

 

197,760,000

198

Neisseria gonorrhoeae

A small number of promising options need investigation to determine best approach

Adolescents and adults age 15 and over

3,669,254

3

20

10

30

330,232,860

330

Parainfluenza viruses

Trivalent, subunit vaccine (must contain fusion protein)

Infants

3,788,337

2

11.25

10

21.25

161,004,323

161

Respiratory syncytial virus

Glycoprotein produced by recombinant DNA technology

Infants

3,788,337

2

11.25

10

21.25

161,004,323

161

 

Attenuated live virus

Infants

3,788,337

1

11.25

10

21.25

80,502,161

81

Rotavirus

Attenuated live bovine virus

Infants

3,788,337

1.5

7.5

10

17.5

99,443,846

99

 

Attenuated live human or reassortment virus

Infants

3,788,337

1.5

7.5

10

17.5

99,443,846

99

Streptococcus group B

Conjugated polysaccharide

Pregnant women for fetuses and neonates

31788,337

1

22.5

10

32.5

123,120,953

123

aSee text for explanation of the assumptions underlying these calcuations. Costs are upper limits; they are not adjusted for anticipated utilization.



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