Cover Image

Not for Sale



View/Hide Left Panel
Provider Acceptance

Provider recognition of H. influenzae type b as a cause of meningitis and other disease states is believed to be reasonably accurate, involving a moderate risk of a range of severe illnesses. Physician perception of the benefits of an adequately tested vaccine with the envisaged efficacy (see Chapter 5) and ability to induce early immunity would be favorable and any barriers (e.g., the number of doses) would be low because efficacy and safety testing could be conducted reasonably easily. Efficacy trials of the vaccine may be in a high risk population, and this may engender some reservations about relevance to the general population.

Cost of Illness

The scope and purpose of the calculations included below are described in Chapters 4 and 7. These calculations are based on certain simplifying procedures and assumptions that have been judged not to compromise their utility for the purposes of this comparative exercise. The total costs should be taken only as a rough approximation of the direct costs of this disease.

Cost of Total Disease Burden

Categories A & B n/a

 

 

Category C

 

 

Meningitis

 

 

# of cases=9,000

 

 

67% of cases typically receive 13 days hospitalization at $400/day

= $

31,356,000

approx. 33% of cases receive 10 days normal hospitalization at $400/day and 3 days ICU at $600/day

= $

17,226,000

100% of cases typically receive diagnostic testing and treatment procedures at rate equivalent to daily inclusive hospital rate

 

 

for 67%, 13 days at $400/day

= $

31,356,000

for 33%, 10 days at $400/day and 3 days at $600/day

= $

17,226,000

[spinal taps, blood chemistries, antibiotics (ampicillin/chloramphenicol), blood cultures, additional cultures, severe cases may require CAT scan]

 

 

100% of cases typically receive 1 follow-up phys. visit at $30

= $

270,000

 

TOTAL

= $

97,434,000



The National Academies | 500 Fifth St. N.W. | Washington, D.C. 20001
Copyright © National Academy of Sciences. All rights reserved.
Terms of Use and Privacy Statement