. "6. Assessing the Likely Utilization of New Vaccines." New Vaccine Development: Establishing Priorities: Volume I, Diseases of Importance in the United States. Washington, DC: The National Academies Press, 1985.
The following HTML text is provided to enhance online
readability. Many aspects of typography translate only awkwardly to HTML.
Please use the page image
as the authoritative form to ensure accuracy.
New Vaccine Development Establishing Priorities, Volume I: Diseases of Importance in the United States
Assessing the Likely Utilization of New Vaccines
The expected health benefits to be derived from the development of a particular vaccine depend not only on the number of potential recipients of the vaccine (i.e., the target population), but also on the proportion of the target population who will actually receive it. This chapter describes the method used to arrive at an estimate of this proportion for each vaccine candidate.
To predict in advance the extent to which a vaccine candidate would be utilized is a difficult task, because vaccine utilization depends on many interrelated and complex factors. These factors include the following:
the effects of statutory interventions such as school or day-care immunization requirements
characteristics of the target population, including its access to health care providers and the ease with which its members can be identified by the health care system (in turn, dependent on size, composition, age, and socioeconomic status of the target population)
characteristics of the vaccine affecting provider utilization (route of administration, storage conditions, shelf-life, cost of delivery, and special procedures required prior to or during vaccination)
characteristics of the vaccine affecting patient acceptance (number of doses, route of administration, and cost)
provider attitudes toward the vaccine, which are affected by perceptions of efficacy, safety, liability, ease of administration, profitability, professional consensus, and patient need or demand
target population attitudes toward the vaccine, which are influenced by perceptions of the likelihood of contracting the disease, its severity if contracted, and the vaccine’s efficacy and safety.
These factors affect each other in ways that are not fully understood or quantifiable. To develop a method of predicting the likely utilization of new vaccines, the committee chose to consider three distinct groups of factors, namely, those influencing vaccine availability, lay attitudes, and provider attitudes.
Below are the first 10 and last 10 pages of uncorrected machine-read text (when available) of this chapter, followed by the top 30 algorithmically extracted key phrases from the chapter as a whole. Intended to provide our own search engines and external engines with highly rich, chapter-representative searchable text on the opening pages of each chapter.
Because it is UNCORRECTED material, please consider the following text as a useful but insufficient proxy for the authoritative book pages.
Do not use for reproduction, copying, pasting, or reading; exclusively for search engines.