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Total Scores

Combined Scores

 

 

 

Lay

Provider

Weighted Additive Scores

Weighted Multiplicative Scores

Pathogen

Vaccine Envisaged

Target Population

Weighted Additive

Weighted Multiplicative (×10−6)

Weighted Additive

Weighted Multiplicative (×10−6)

Additive

Multiplicative

Additive (×10−6)

Multiplicative (×10−72)

Herpes simplex viruses 1 & 2

Glycoprotein produced by recombinant DNA technology

Children up to age 12 and other susceptibles

14

0.61

18

1.54

32

252

2.15

0.9394

 

Attenuated live virus

Children up to age 12 and other susceptibles

14

0.61

12

0.56

26

168

1.17

0.3416

Herpesvirus varicellae

Attenuated live virus

Recipients of organ and bone marrow transplants and persons under age 25 with leukemias and lymphomas

41

35.42

33

13.43

74

1353

48.85

475.6906

 

 

Normal susceptibles, routine for children (booster for adults)

24

2.25

18

0.56

42

432

2.81

1.26

Influenza viruses A & B

Subunit vaccine (purified hemagglutinin/ neuraminidase proteins)

High-risk population as currently defined (see Appendix K)

10

0.35

16

1.07

26

160

1.42

0.3745

 

Attenuated live virus

High-risk population as currently defined (see Appendix K)

13

0.6

16

1.07

29

208

1.67

0.642

Neisseria gonorrhoeae

A small number of promising options need investigation to determine best approach

Adolescents and adults age 15 and over

5

0.085

15

0.66

20

75

0.745

0.0561

Parainfluenza viruses

Trivalent, subunit vaccine (must contain fusion protein)

Infants

19

0.68

25

4.74

44

475

5.42

3.2232

Respiratory syncytial virus

Glycoprotein produced by recombinant DNA technology

Infants

12

0.41

19

1.7

31

228

2.11

0.697

 

Attenuated live virus

Infants

18

1.38

21

2.3

39

378

3.68

3.174

Rotavirus

Attenuated live bovine virus

Infants

14

0.64

17

0.68

31

238

1.32

0.4352

 

Attenuated live human or reassortment virus

Infants

14

0.64

17

0.68

31

238

1.32

0.4352

Streptococcus group B

Conjugated polysaccharide

Pregnant women for fetuses and neonates

6

0.041

20

1.57

26

120

1.611

0.06437



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