Challenges to scientific understanding: Wide selection of biological multifunctional systems to drive inspiration of new designs with advanced materials properties (e.g., strength, adhesion, optics, hierarchy, assembly)
Opportunity: Enriching and harvesting underlying principles and processes to drive engineering activities in a productive way
Opportunity: Fabrication and assembly of inspired materials
Challenges to scientific understanding: Biomimicry of biomolecules with directed conformation and information content
Opportunity: Defining desired properties and designing controlled synthesis
Opportunity: Characterization and implementation of new materials
Challenges to scientific understanding: Seamless integration of functionalized biomolecular materials in the body and in devices
Opportunity: Preventing fouling and foreign-body reaction from functionalized biomaterials
Opportunity: Controlling reactions at the surface to optimize desired integration of material
Opportunity: Longevity and robustness
Department of Energy, Basic Research Needs for Solar Energy Utilization, Washington, D.C., 2005. Available online at http://www.sc.doe.gov/bes/reports/files/SEU_rpt.pdf. Last accessed March 26, 2008.
Gellman, S.H. “Foldamers: A manifesto,” Accounts of Chemical ResearchChemical Research 31:173-180 (1998).
Humayun, M.S., J.D. Weiland, G. Chader, and E. Greenbaum (editors), Artificial Sight: Basic Research, Biomedical Engineering, and Clinical Advances, New York, N.Y., Springer, 2007.
Jung, C.C., E.W. Saaski, D.A. McCrae, B.M. Lingerfelt, and G.P. Anderson, “RAPTOR: A fluoroimmunoassay-based fiber optic sensor for detection of biological threats,” Sensors Journal, IEEE 3(4):352-360 (2003).
Langer, R. “Drug delivery: Drugs on target,” Science 293:58-59 (2001).
Langer, R., and N.A. Peppas, “Advances in biomaterials, drug delivery, and bionanotechnology,” American Institute of Chemical Engineers Journal 49(12):2990-3006 (2003).
Mann, S., Biomineralization: Principles and Concepts, Oxford University Press, 2001.
National Research Council, The New Science of Metagenomics: Revealing the Secrets of Our Microbial Planet, Washington, D.C., The National Academies Press, 2007.
National Research Council, Polymer Science and Engineering: The Shifting Research Frontiers, Washington, D.C., National Academy Press, 1994.
Pollard, T.D., W.C. Earnshaw, and J. Lippincott-Schwartz, Cell Biology, 2nd Ed., Saunders, 2007, Chapters 36-39.
Raber, E., A. Jin, K. Noonan, R. McGuire, and R.D. Kirvel, “Decontamination issues for chemical and biological warfare agents: How clean is clean enough?” International Journal of Environmental Health Research 11(2):128-148 (2001).
Ragauskas, A.J., C.K. Williams, B.H. Davison, G. Britovsek, J. Cairney, C.A. Eckert, W.J. Frederick, Jr., J.P. Hallett, D.J. Leak, C.L. Liotta, J.R. Mielenz, R. Murphy, R. Templer, and T. Tschaplinski, “The path forward for biofuels and biomaterials,” Science 311:484-489 (2006).