research that will lead to new technologies and drugs, particularly in areas of cognition and performance, that will include off-label uses. Off-label drug use can alert intelligence analysts to compounds, methods of administration, or risk factors that may be unknown in civilian or military medicine and can help identify profiles of unanticipated effects.


Key Finding (Finding 5-4). Rapid advances in cognitive neuroscience, as in science and technology in general, represent a major challenge to the IC. The IC does not have the internal capability to warn against scientific developments that could lead to major—even catastrophic—intelligence failures in the years ahead. An effective warning model must depend on continuous input from strong internal science and technology programs, strong interactive networks with outside scientific experts, and government decision makers who engage in the process and take it seriously as a driver of resources. All that remains a work in progress for the IC.

REFERENCES

Council for International Organizations of Medical Sciences. 2002. International Ethical Guidelines for Biomedical Research Involving Human Subjects. Geneva, Switzerland, November 2002. Available from http://www.cioms.ch/guidelines_nov_2002_blurb.htm. Last accessed June 8, 2008.

National Research Council (NRC). 2003. The Polygraph and Lie Detection. Washington, DC: The National Academies Press. Available from http://www.nap.edu/catalog.php?record_id=10420.

NRC. 2005. Avoiding Surprise in an Era of Global Technology Advances. Washington, DC: The National Academies Press. Available from http://www.nap.edu/catalog.php?record_id=11286.

Thomas, J.J., and K.A. Cook. 2005. Illuminating the path: The research and development agenda for visual analytics. Richland, WA: National Visualization and Analytics Center. Available from http://nvac.pnl.gov/agenda.stm#book. Last accessed January 10, 2008.

United Nations. 1948. Universal Declaration of Human Rights. Adopted and proclaimed by General Assembly Resolution 217 A (III) of 10 December 1948. Palais de Chaillot, Paris, December 1948. Available from http://www.un.org/Overview/rights.html.

World Medical Association. 1964. Declaration of Helsinki: Ethical Principles for Medical Research Involving Human Subjects. Adopted by the 18th World Medical Association General Assembly. Helsinki, Finland, June 1964. Available from http://www.wma.net/e/policy/b3.htm.



The National Academies | 500 Fifth St. N.W. | Washington, D.C. 20001
Copyright © National Academy of Sciences. All rights reserved.
Terms of Use and Privacy Statement