. "Letter Report." Assessment of the Role of Intermittent Preventive Treatment for Malaria in Infants: Letter Report. Washington, DC: The National Academies Press, 2008.
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Assessment of the Role of Intermittent Preventive Treatment for Malaria in Infants: Letter Report
TABLE 10 Incidence of Malaria During the Inter-Dose 1 Perioda
Location, Country
Ifakara, Tanzania
Navrongo, Ghana
Manhiça, Mozambique
Kumasi, Ghana
Lambaréné, Gabon
Tamale, Ghana
Placebo
Episodes
47
464
142
248
32
241
PYAR
99
580
184
184
173
200
Incidence
0.47
0.80
0.77
1.4
0.19
1.0
IPTi with SP
Episodes
29
412
154
219
28
166
PYAR
102
578
194
184
173
201
Incidence
0.28
0.71
0.80
1.2
0.16
0.83
Efficacy (95% CI)
42 (−1, 67)
11 (−8, 26)
−2 (−37, 24)
11 (−6, 26)
14 (−56, 53)
19 (−1, 35)
p-value
0.055
0.23
0.88
0.19
0.61
0.064
NOTE: PYAR: Person-years at risk.
a The Inter-dose 1 period extends from 35 days after (a) dose 2 (age 3 months) in Ifakara; (b) dose 2 (age 4 months) in Navrongo and Manhiça; (c) dose 1 (age 3 months) in Kumasi, Lambaréné, and Tamale until the next dose of IPTi administered at 9 months of age.
SOURCE: Reprinted with permission from the Statistical Working Group (IPTi Consortium, 2007b).
