medicines and all medical and paramedical interventions; to improve public health and safety in relation to the use of medicines; and to contribute to the assessment of benefit, harm, effectiveness and risk of medicines, encouraging their safe, rational, and more effective (including cost-effective) use; and to effective communication to the public.

Splenomegaly—An enlarged spleen; a common finding in malaria patients that can sometimes be detected by physical examination of the abdomen.