presence of a potential threshold concentration of ozone below which mortality effects are not observable. EPA should present multiple results from each study and characterize the different sources of error in the studies in a final uncertainty estimation on their benefits analysis.

  • Air-quality numeric models (such as CMAQ) should be considered for use in ozone epidemiologic studies to extend the spatial scale of available data. However, the uncertainty associated with the models needs to be carefully considered before inferences are drawn from the simulation models for mortality risk assessment.

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