The following HTML text is provided to enhance online
readability. Many aspects of typography translate only awkwardly to HTML.
Please use the page image
as the authoritative form to ensure accuracy.
Epidemiologic Studies of Veterans Exposed to Depleted Uranium: Feasibility and Design Issues
The committee made several additional recommendations:
DOD should investigate available in vivo assay techniques other than measuring urinary uranium to determine whether they offer advantages (for example, increased sensitivity) over urinalysis.
DOD should consider assessing uranium concentrations in lung, kidney, and brain tissues from military personnel who were potentially exposed to DU and died while on active duty. Analysis of uranium in autopsy tissue might provide information on concordance between renal uranium concentrations and model-based estimates. It also would provide information on pulmonary retention of DU, which has implications for estimating lung cancer risk, and insight into the toxicokinetics of DU.
DOD should continue to link and integrate available databases so that information can be assessed.
DOD should determine the feasibility of collecting biomarker data from people in the Millennium Cohort Study who reported being exposed to DU and from military personnel who were at Camp Doha during the time of the fire in 1991. Any study participants who have positive bioassay results for DU exposure should receive health monitoring through the Depleted Uranium Follow-Up Program at the BVAMC throughout their lifespans.
DOD should conduct further study of the potential reproductive and developmental toxicity of DU with animal models.