• Does the proposed study use appropriate sampling, estimation, and analysis methods to obtain the most useful data and results from the study?

  • Does it give appropriate attention to the challenges for standardized data collection from a decentralized operation in which study centers implement sampling, enrollment, and data collection?

  • Does the research plan provide information on the NCS data collection strategies to maximize initial and follow-up study response rates to ensure quality data collection?

  • Does the research plan address appropriate analytic and data dissemination approaches to ensure that the study research goals are achieved?

Chapter 5 addresses ethical issues for the NCS. It addresses the following questions:

  • Does the proposed study provide adequate protections for human research participants?

  • Does it include plans for releasing data to the research community in a manner that maximizes what can be learned from the data, at the same time protecting the confidentiality of NCS research participants?

Chapter 6 lists the panel’s conclusions and recommendations in one place for ease of reference.

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