Does the proposed study use appropriate sampling, estimation, and analysis methods to obtain the most useful data and results from the study?
Does it give appropriate attention to the challenges for standardized data collection from a decentralized operation in which study centers implement sampling, enrollment, and data collection?
Does the research plan provide information on the NCS data collection strategies to maximize initial and follow-up study response rates to ensure quality data collection?
Does the research plan address appropriate analytic and data dissemination approaches to ensure that the study research goals are achieved?
Chapter 5 addresses ethical issues for the NCS. It addresses the following questions:
Does the proposed study provide adequate protections for human research participants?
Does it include plans for releasing data to the research community in a manner that maximizes what can be learned from the data, at the same time protecting the confidentiality of NCS research participants?
Chapter 6 lists the panel’s conclusions and recommendations in one place for ease of reference.