Gulf War and Health: Volume 7: Long-Term Consequences of Traumatic Brain Injury

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Gulf War and Health: Volume 7: Long-Term Consequences of Traumatic Brain Injury (2008)
Board on Population Health and Public Health Practice (BPH)

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. "5 MAJOR COHORT STUDIES." Gulf War and Health: Volume 7: Long-Term Consequences of Traumatic Brain Injury. Washington, DC: The National Academies Press, 2008.

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Gulf War and Health, Volume 7: Long-Term Consequences of Traumatic Brain Injury

Reference	Purpose	Study Design	Population (Where Appropriate)			Comments
			Eligible	Located	Enrolled (Response Rate)
Bryant and Harvey, 1999a	Influence of mild TBI on acute stress disorder, PTSD	Prospective	222 patients admitted during 10-mo period; 79 patients with TBI, 92 without TBI included in study; at 6-mo followup, 63 (80%) mild-TBI patients, 71 (77%) non-TBI patients eligible
Harvey and Bryant, 2000	Relationship between acute stress disorder and PTSD after MTBI	Prospective	2-year assessment of mild-TBI study population from Bryant 1998; 50 mild-TBI patients captured (63% retention rate from original population, 79% retention from 6-mo population)
Bryant and Harvey, 1999b	PTSD, PCS	Prospective	145 of admitted patients during study period; 46 mild-TBI patients, 59 no-TBI patients captured at 6-mo assessment (83% of eligible sample)

Reference	Eligible Population	Type of Study or Methods	Date(s) of Enrollment	Subgroup (n= Eligible Subjects)	Contacted or Located (% of Eligible)	Responded or Enrolled (Response Rate)	Comments
University of Washington Longitudinal Traumatic Brain Injury Studies
Behavioral Outcome in Head Injury, McLean et al., 1993	Consecutively admitted adults to Level I trauma center at Harborview; subjects met following criteria: any period of loss of consciousness, PTA for at least 1 h, or other objective evidence of head trauma; injury had to require hospitalization; age range, 15–60 years; patients with preexisting conditions excluded; 102 friend controls included in study	Prospective cohort	1980–1982	102			English-speaking adults; enrolled at time of injury and prospectively followed to 1 year; of 102 enrolled and examined at 1 month, 97 examined at 1 year