for >1 TBI in men with glioma (OR, 1.52; 95% CI, .00–2.32) but not seen in women or men with meningioma

No correlation with sports participation

Risk of meningioma in men higher 15-24 years after trauma (OR, 5.35; 95% CI, 1.72–16.62)

Schlehofer et al., 1992.

Population-based case–control

226 cases in Rhein-Neckar-Odenwald area of Germany with primary brain tumors diagnosed 1987–1988; controls, 418 randomly selected from residential registers

Self-reported history of head injury requiring medical attention; obtained by interview

Primary brain tumors (ICD-9 191, 191.1, 192.0), restricted to gliomas (115), meningiomas (81), acoustic neuromas (30)

For all tumor types: 46 of 226 (20%) vs 113 of 418 (27%); RR, 0.71 (95% CI, 0.5–1.1)

Age-, sex-matching for controls

418 of 521 (72%) potential controls participated; self-reports of head trauma; no comparisons by severity or number of injuries

For gliomas: 27 cases vs 66 controls; RR, 0.70 (95% CI, 0.4–1.2)

For meningiomas: 13 cases vs 39 controls; RR, 0.52 (95% CI, 0.3–1.0)