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Abbreviations ACGIH American Conference of Governmental Industrial Hygienists AEGL-1 The airborne concentration (expressed as ppm [parts per million] or mg/m3 [milligrams per cubic meter]) of a substance above which it is predicted that the general population, including susceptible individuals, could experience notable discomfort, irritation, or certain asymptomatic nonsensory effects. However, the effects are not disabling and are transient and reversible upon cessation of exposure AEGL-2 The airborne concentration (expressed as ppm or mg/m3) of a substance above which it is predicted that the general population, including susceptible individuals, could experience irreversible or other serious, long-lasting adverse health effects or an impaired ability to escape AEGL-3 The airborne concentration (expressed as ppm or mg/m3) of a substance above which it is predicted that the general population, including susceptible individuals, could experience life-threatening adverse health effects or death AEGLs acute exposure guideline levels ATSDR Agency for Toxic Substances and Disease Registry BALF bronchoalveolar lavage fluid BSP bromosulfophthalein BUN blood urea nitrogen CD50 coma induction in 50% of subjects CEELs community emergency exposure levels CNS central nervous system DFG Deutsche Forschungsgemeinschaft DOD U.S. Department of Defense DOE U.S. Department of Energy EHS extremely hazardous substance EPA U.S. Environmental Protection Agency ERPG emergency response planning guidelines ETO ethylene oxide FEV1 forced expiratory volume in the first second h hour HNO3 nitric acid IDLH immediately dangerous to life and health JP-8 jet fuel (or jet propellant) number 8 LC50 concentration of a substance that is lethal to 50% of test organisms in a given time LD50 dose of a substance that is lethal to 50% of test organisms in a given time LOA level of distinct odor awareness LPS lipopolysaccharide m3 cubic meters MAK maximale argeitsplatzkonzentration [maximum workplace concentration] MEK methyl ethyl ketone mg milligram 37
min minute NAC National Advisory Committee on Acute Exposure Guideline Levels for Hazardous Substances NIOSH National Institute for Occupational Safety and Health NO nitric oxide NO2 nitrogen dioxide NOAEL no-observed-adverse-effect level NOEL no-observed-effect level NRC National Research Council NTP National Toxicology Program ORNL Oak Ridge National Laboratory PBPK physiologically based pharmacokinetic PHA phytohemagglutinin PMN polymorphonuclear leukocyte ppm parts per million RBC red blood cell RD50 concentration of a substance that reduced the respiratory rate of test organisms by 50% RFNA red fuming nitric acid SAR structure-activity relationship SOP standard operating procedure STEL short-term exposure limit STV short-term value TLV Threshold Limit Value TSD technical support document UF uncertainty factor URL uniform resource locator for the Internet WEEL workplace environmental exposure limit WFNA white fuming nitric acid 38