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Combined Exposures to Hydrogen Cyanide and Carbon Monoxide in Army Operations: Final Report (2008)

Chapter: Appendix A: Biographical Information on the Committee on Combined Exposures to Hydrogen Cyanide and Carbon Monoxide in Army Operations

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Suggested Citation:"Appendix A: Biographical Information on the Committee on Combined Exposures to Hydrogen Cyanide and Carbon Monoxide in Army Operations." National Research Council. 2008. Combined Exposures to Hydrogen Cyanide and Carbon Monoxide in Army Operations: Final Report. Washington, DC: The National Academies Press. doi: 10.17226/12467.
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Suggested Citation:"Appendix A: Biographical Information on the Committee on Combined Exposures to Hydrogen Cyanide and Carbon Monoxide in Army Operations." National Research Council. 2008. Combined Exposures to Hydrogen Cyanide and Carbon Monoxide in Army Operations: Final Report. Washington, DC: The National Academies Press. doi: 10.17226/12467.
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Page 30
Suggested Citation:"Appendix A: Biographical Information on the Committee on Combined Exposures to Hydrogen Cyanide and Carbon Monoxide in Army Operations." National Research Council. 2008. Combined Exposures to Hydrogen Cyanide and Carbon Monoxide in Army Operations: Final Report. Washington, DC: The National Academies Press. doi: 10.17226/12467.
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Page 31

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Appendix A Biographical Information on the Committee on Combined Exposures to Hydrogen Cyanide and Carbon Monoxide in Army Operations William E. Halperin is professor and chair of the Department of Preventive Medicine and Community Health at the UMDNJ–New Jersey Medical School. He received his M.D., M.P.H., and Dr.P.H. from Harvard University. Previously, Dr. Halperin was deputy director of the National Institute for Occupa- tional Safety and Health. His research interests are in occupational medicine, occupational epidemiology, and public health surveillance. Dr. Halperin was a member of the National Research Council (NRC) Committee on Risk Assessment Methodology and served as a member of the Committee on Toxicology’s Subcommittee on Spacecraft Water Exposure Guidelines; Subcommittee on Ethylene Oxide; and Sub- committee on Jet Fuels, Panel on Emergency Exposure Guidance Levels. He also served as a member of the Institute of Medicine’s Committee to Survey the Health Effects of Mustard Gas and Lewisite. Dr Halperin is certified by the American Board of Preventive Medicine and the American Board of Occupa- tional Medicine. He is currently the chair of the NRC Committee on Toxicology. Gary P. Carlson is professor of toxicology and former associate head of the School of Health Sciences at Purdue University. He received his Ph.D. in pharmacology from the University of Chicago. He is cur- rently serving on the NRC Committee on Toxicology. Previously, he was chair of the NRC Committee on Toxicology’s Subcommittee on Toxicologic Assessment of Low-Level Exposures to Chemical War- fare Agents. Dr. Carlson has served as secretary of the Society of Toxicology, chair of the society’s Edu- cation Committee, and chair of its Board on Publications. He has served on the U.S. Environmental Pro- tection Agency (EPA) Joint Advisory Board–Science Advisory Panel Committees on (1) Cholinesterase Inhibition and (2) Cholinesterase and Aldicarb and on the EPA Science Advisory Board’s Panel on Drinking Water. Dr. Carlson has also served on the Board of Scientific Counselors of the National Toxi- cology Program (NTP) and as chair of the NTP Technical Reports Review Committee. He is an associate editor of the Journal of Toxicology and Environmental Health and serves on the editorial board of the Journal of Toxicology. Ronald F. Coburn is professor of physiology at the University of Pennsylvania. He received his M.D. from Northwestern University in 1957. He has done extensive research on carbon monoxide. He was the chairman of the Panel on Carbon Monoxide from 1972 to 1975. He received the National Institutes of Health Merit Award in 1997. He previously served on the NRC Committee on Medical and Biological Effects of Air Pollutants (1972-1976). Dr. Coburn has served on many editorial boards including Physio- logical Review, American Journal of Physiology, and Journal of Applied Physiology. 29

Combined Exposures to HCG and CO in Army Operations: Final Report James E. Dennison is a certified industrial hygienist and owner of Century Environmental Hygiene LLC, Fort Collins, CO. Dr. Dennison received his Ph.D. in Environmental Health Toxicology from Colorado State University. His doctoral thesis involved physiologically based pharmacokinetic modeling (PBPK) of complex mixtures of gasoline in rats. He has worked with the National Advisory Committee on Acute Exposure Guideline Levels (AEGLs) performing PBPK modeling of central-nervous-system depressants to help establish AEGL values for several chemicals. He performs consulting work as a certified indus- trial hygienist providing advice on testing, evaluation, and control of chemical agents, such as heavy met- als, solvents, pesticides, and biological materials. He currently serves as the vice chair of the Biological Monitoring Committee of the American Industrial Hygiene Association. Jeffrey W. Fisher is co-director of the Center for Security of Agriculture and the Environment. He is also department head and professor in the Department of Environmental Health Science, College of Agri- cultural and Environmental Sciences at the University of Georgia (UGA). He joined UGA in 2000 and served as department head of the Department of Environmental Health Science from 2000 to 2006. He now serves as director of the Interdisciplinary Toxicology Program at UGA. He spent most of his career at the Toxicology Laboratory, Wright-Patterson Air Force Base, where he was principal investigator and senior scientist in the Toxics Hazards Division and technical advisor for the Operational Toxicology Branch. Dr. Fisher’s research interests are in the development and application of biologically based mathematical models to ascertain health risks from environmental and occupational chemical exposures. His modeling experience includes working with chlorinated and nonchlorinated solvents, fuels, PCB, py- rethroids and perchlorate. Dr. Fisher has published over 100 papers on pharmacokinetics and PBPK mod- eling in laboratory animals and humans. He has served on several panels and advisory boards for the DOD, Agency for Toxic Substances and Disease Registry, EPA, and nonprofit organizations. He is a member of the NRC Committee on Toxicology’s Committee on Acute Exposure Guideline Levels (2004 to present) and is a fellow of the Academy of Toxicological Sciences. James J. McGrath is professor emeritus at Texas Tech University Health Sciences Center, Lubbock. He received his Ph.D. from Indiana University in 1968. Dr. McGrath served at EPA’s Office of Risk As- sessment and was awarded a Silver Star in recognition of work in evaluating the world’s health and toxi- cology literature for relevancy to standard setting for diesel exhausts and worked on Air Quality Criteria for Carbon Monoxide. He also served as a consultant for indoor air quality for EPA’s new campus. He served as a principal author for EPA’s Air Quality Criteria for Particulate Matter. He is serving (or has served) on the editorial boards of American Journal of Physiology, Science, Molecular Pharmacology, Journal of Applied Toxicology, Journal of Toxicology and Environmental Health, Toxicology Letters, and CRC Press. He has served on the Society of Toxicology’s inhalation toxicology specialty section. Chiu-Wing Lam is a senior scientist–toxicologist with Wyle Laboratories in Houston, working for the Johnson Space Center Toxicology Group. He received his Ph.D. in toxicology from the University of Rochester in 1983. He is a diplomat of the American Board of Toxicology. He has drafted numerous toxi- cologic risk assessment documents on spacecraft maximum allowable concentrations (SMACs) since 1990. The SMAC values (for time durations ranging from 1 hour to 180 days) are valuable guidelines to the National Aeronautics and Space Administration for assessing air quality in its space station and space shuttle documents. He also drafted the hydrogen cyanide SMAC document. Dr. Lam has conducted nu- merous toxicologic assessments of payload and utility chemicals used in space shuttles and space stations, providing consultations to NASA flight surgeons, safety engineers, and payload customers on toxicologic issues, including toxicities of potential combustion products of nonmetallic materials used in the space- craft. George C. Rodgers is professor of pediatrics at the University of Louisville. He received his Ph.D. in 1964 from Yale University and received his M.D. in 1975 from the State University of New York, Syra- cuse. He is board certified in pediatrics and medical technology. He is a member of the National Advisory 30

Appendix A Committee on Acute Exposure Guideline Levels; he was the chemical manager for the carbon monoxide AEGLs document that was reviewed by the NRC. He also served on the American Society of Safety En- gineers, Z390: Accredited Standards Committee on Hydrogen Sulfide Safety Training. Dr. Rodgers is a fellow of the American College of Medical Toxicology. He is on the editorial board of Poisindex. He was a member of the Firefigthers Safety Act Technical Committee and was president of the American Asso- ciation of Poison Control Centers. He has served on committees of governmental agencies, such as EPA, ATSDR, and the Centers for Disease Control and Prevention. Sylvia Talmage is a senior toxicologist at Summitec Corporation, a contractor for Oak Ridge National Laboratory. She received her Ph.D. from the University of Tennessee. She is a diplomat of the American College of Toxicology. She served on the NRC Subcommittee for the Review of the Risk Assessment of Methyl Bromide. She previously served for 26 years at Oak Ridge National Laboratory, where she per- formed numerous toxicologic risk assessments for hazardous chemicals. She is the author of numerous acute exposure guideline level (AEGL) documents that were reviewed by the NRC. She also drafted the hydrogen cyanide AEGL document. She has provided advice to EPA and the U.S. Army on matters re- lated to toxicology and risk assessment. 31

Next: Appendix B: Previous Applications of the Coburn-Forster-Kane Equation to Predict Carboxyhemoglobin Levels Resulting from Varying Carbon Monoxide Exposures »
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To determine whether the air quality inside armored-vehicle cabins can meet exposure guidelines under deployment conditions, the Army assessed possible synergistic toxic effects from potentially harmful substances. This book, the final of two reports on the subject from the National Research Council, addresses whether the approach discussed in the technical context section of the Army's proposed guidance is appropriate, or whether an alternative assessment method should be developed.

Combined Exposures to Hydrogen Cyanide and Carbon Monoxide in Army Operations provides several conclusions and recommendations, including the use of alternative instrumentation for monitoring gas, conducting experiments on human subjects, and seeking advice from additional groups involved with personnel training and field deployment.

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