TABLE E-2 Risk Factors for Schizophrenia

Developmental Period

Context

Individual

Family

School and Peers

Neighborhood

Preconception/prenatal

Genetic predisposition2,3,4,5

2nd generation immigrant1,3

Problems during pregnancy (diabetes and bleeding)3,4

Problems with fetal growth and development4,5

Maternal stress during pregnancy (such as spousal death)3,4

Maternal infection or flu exposure during pregnancy2,4,5

Hypoxia-related delivery complications2,3,4,5

Male gender3,5

Parental diagnosis of schizophrenia2,4,5

 

Urban setting1,3,4

Low SES1

Infancy

Head injury2

 

 

Urban setting1,3,4

Social adversity1

Early childhood

Head injury2

Motor, language, and cognitive impairments3,4

Family dysfunction1

 

Urban setting1,3,4

Social adversity1

Middle childhood

Head injury2

Self-reported psychotic symptoms4

Family dysfunction1

 

Urban setting1,3,4

Social adversity1

Adolescence

Head injury2

Cannabis use3,4

Family dysfunction1

 

Urban setting1,3,4

Social adversity1



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