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Blaese, R.M., K.W. Culver, A.D. Miller, C.S. Carter, T. Fleisher, M. Clerici, G. Shearer, L. Chang, Y. Chiang, P. Tolstoshev, J.J. Greenblatt, S.A. Rosenberg, H. Klein, M. Berger, C.A. Mullen, W.J. Ramsey, L. Muul, R.A. Morgan, and W.F. Anderson. 1995. T lymphocyte-directed gene therapy for ADA-SCID: initial trial results after four years. Science 270(5235): 475–480.

Boussif, O., F. Lezoualch, M.A. Zanta, M.D. Mergny, D. Scherman, B. Demeneix, and J.P. Behr. 1995. A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine. Proceedings of the National Academy of Sciences of the United States of America 92(16): 7297–7301.

Cavazzana-Calvo, M., S. Hacein-Bey, G. de Saint Basile, F. Gross, E. Yvon, P. Nusbaum, F. Selz, C. Hue, S. Certain, J.L. Casanova, P. Bousso, F.L. Deist, and A. Fischer. 2000. Gene therapy of human severe combined immunodeficiency (SCID)-X1 disease. Science 288(5466): 669–672.

Felgner, P.L., and A. Rolland. 1998. Non-viral gene delivery systems. Advanced Drug Delivery Reviews 30(1-3): 1–3.

Forrest, M.L., J.T. Koerber, and D.W. Pack. 2003. A degradable polyethylenimine derivative with low toxicity for highly efficient gene delivery. Bioconjugate Chemistry 14(5): 934–940.

Forrest, M.L., G.E. Meister, J.T. Koerber, and D.W. Pack. 2004. Partial acetylation of polyethylenimine enhances in vitro gene delivery. Pharmaceutical Research 21(2): 365–371.

Gabrielson, N.P., and D.W. Pack. 2006. Acetylation of polyethylenimine enhances gene delivery via weakened polymer/DNA interactions. Biomacromolecules 7(8): 2427–2435.

Green, J.J., R. Langer, and D.G. Anderson. 2008. A combinatorial polymer library approach yields insight into nonviral gene delivery. Accounts of Chemical Research 41(6): 749–759.

Kay, M.A., C.S. Manno, M.V. Ragni, P.J. Larson, L.B. Couto, A. McClelland, B. Glader, A.J. Chew, S.J. Tai, R.W. Herzog, V. Arruda, F. Johnson, C. Scallan, E. Skarsgard, A.W. Flake, and K.A. High. 2000. Evidence for gene transfer and expression of factor IX in haemophilia B patients treated with an AAV vector. Nature Genetics 24(3): 257–261.

Khuri, F.R., J. Nemunaitis, I. Ganly, J. Arseneau, I.F. Tannock, L. Romel, M. Gore, J. Ironside, R.H. MacDougall, C. Heise, B. Randlev, A.M. Gillenwater, P. Bruso, S.B. Kaye, W.K. Hong, and D.H. Kirn. 2000. A controlled trial of intratumoral ONYX-015, a selectively-replicating adenovirus, in combination with cisplatin and 5-fluorouracil in patients with recurrent head and neck cancer. Nature Medicine 6(8): 879–885.

Lim, Y.-B., C.-H. Kim, K. Kim, S.W. Kim, and J.-S. Park. 2000. Development of a safe gene delivery system using biodegradable polymer, poly[α-(4-aminobutyl)-l-glycolic acid]. Journal of the American Chemical Society 122(27): 6524–6525.

Pack, D.W., A.S. Hoffman, S. Pun, and P.S. Stayton. 2005. Design and development of polymers for gene delivery. Nature Reviews. Drug Discovery 4(7): 581–593.

Smith, J., Y. Zhang, and R. Niven. 1997. Toward development of a non-viral gene therapeutic. Advanced Drug Delivery Reviews 26(2-3): 135–150.

Verma, I.M., and N. Somia. 1997. Gene therapy—promises, problems and prospects. Nature 389(6648): 239–242.

Wu, G.Y., and C.H. Wu. 1987. Receptor-mediated in vitro gene transformation by a soluble DNA carrier system. Journal of Biological Chemistry 262(10): 4429–4432.

Zauner, W., M. Ogris, and E. Wagner. 1998. Polylysine-based transfection systems utilizing receptor-mediated delivery. Advanced Drug Delivery Reviews 30(1-3): 97–113.

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