NRC (National Research Council). 2000. Methods for Developing Spacecraft Water Exposure Guidelines. Washington, DC: National Academy Press.

NTP (National Toxicology Program). 1991. Toxicity Studies of 1,2-Dichloroethane (Ethylene Dichloride) (CAS No. 107-06-2) in F344/N Rats, Sprague Dawley Rats, Osborne-Mendel Rats, and B6C3F1 Mice (Drinking Water and Gavage Studies). NTP TOX 4. NIH Publication No. 91-3123. National Toxicology Program, U.S. Department of Health and Human Services, Public Health Service, National Institutes of Health, Research Triangle Park, NC.

NTP (National Toxicology Program). 2005. 1,2-Dichloroethane (Ethylene Dichloride) CAS No. 107-06-2. In Report on Carcinogens, 11th Ed. U.S. Department of Health and Human Services, Public Health Service, National Toxicology Program [online]. Available: http://ntp.niehs.nih.gov/ntp/roc/eleventh/profiles/s065dich.pdf [accessed Oct. 4, 2007].

Reitz, R.H., T.R. Fox, J.C. Ramsey, J.F. Quast, P.W. Langvardt, and P.G. Watanabe. 1982. Pharmacokinetic and macromolecular interactions of ethylene dichloride in rats after inhalation or gavage. Toxicol. Appl. Pharmacol. 62(2):190-204.

Rannug, U., A. Sundvall, and C. Ramel. 1978. The mutagenic effect of 1,2-dichloroethane on Salmonella typhimurium I. Activation through conjugation with glutathion in vitro. Chem. Biol. Interact. 20(1):1-16.

Sherwood, R.L., W. O’Shea, P.T. Thomas, H.V. Ratajczak, C. Aranyi, and J.A. Graham. 1987. Effects of inhalation of ethylene dichloride on pulmonary defenses of mice and rats. Toxicol. Appl. Pharmacol. (3):491-496.

Spencer, H.C., V.K. Rowe, E.M. Adams, D.D. McCollister, and D.D. Irish. 1951. Vapor toxicity of ethylene dichloride determined by experiments on laboratory animals. Ind. Hyg. Occup. Med. 4(5):482-493.

Spreafico, F., E. Zuccato, F. Marcucci, M. Sironi, S. Paglialunga, M. Madonna, and E. Mussini. 1980. Pharmacokinetics of ethylene dichloride in rats treated by different routes and its long-term inhalatory toxicity. Pp. 107-133 in Ethylene Dichloride: A Potential Health Risk? B. Ames, P. Infante, and R. Reitz, eds. Banbury Report 5. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press.

Storer, R.D., N.M. Jackson, and R.B. Conolly. 1984. In vivo genotoxicity and acute hepatotoxicity of 1,2-dichloroethane in mice: Comparison of oral, intraperitoneal, and inhalation routes of exposure. Cancer Res. 44(10):4267-4271.

Tafazoli, M., A. Baeten, P. Geerlings, and M. Kirsch-Volders. 1998. In vitro mutagenicity and genotoxicity study of a number of short-chain chlorinated hydrocarbons using the micronucleus test and the alkaline single cell gel electrophoresis technique (Comet assay) in human lymphocytes: A structure-activity relationship (QSAR) analysis of the genotoxic and cytotoxic potential. Mutagenesis 13(2):115-126.

Taylor, G.R. 1993. Immune changes during short-duration missions. J. Leukoc. Biol. 54(3):202-208.

Ward, J.M. 1980. The carcinogenicity of ethylene dichloride in Osborne-Mendel rats and B6C3F1 mice. Pp. 35-53 in Ethylene Dichloride: A Potential Health Risk? B. Ames, P. Infante, and R. Reitz, eds. Banbury Report 5. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press.

WHO (World Health Organization). 1996. Guidelines for Drinking-Water Quality Criteria, 2nd Ed., Vol. 2. Health Criteria and Other Supporting Information. Geneva, Switzerland: World Health Organization.

Wong, K.L. 1996. 1,2-Dichloroethane. Pp.135-170 in Spacecraft Maximum Allowable Concentrations for Selected Airborne Contaminants, Vol. 3. Washington DC: National Academy Press.



The National Academies | 500 Fifth St. N.W. | Washington, D.C. 20001
Copyright © National Academy of Sciences. All rights reserved.
Terms of Use and Privacy Statement