TABLE C-6 DNA, Glycogen, and Lipid Content in Placentas from Normal and Diabetic Human Pregnancies

Pregnancy

Placental Weight (g)

Placental DNA

Placental Glycogen

Placental Lipid Triglycerides

(mg/g)

(g/total placenta)

(mg/g)

(mg/mg DNA)

(g/total placenta)

(μmol/g)

(μmol/mg DNA)

(mmol/total placenta)

Normal (n = 50)

550 ± 28

2.54 ± 0.13

1.40 ± 0.07

8.4 ± 0.5

3.3 ± 0.3

4.67 ± 0.29

2.51 ± 0.16

0.98 ± 0.15

1.38 ± 0.10

Gestational diabetes (n = 23)

664 ± 60

2.58 ± 0.24

1.71a ± 0.12

9.9 ± 0.8

3.8 ± 0.4

6.57a ± 0.60

3.32a ± 0.31

1.29 ± 0.20

2.20a ± 0.25

Insulin-treated diabetes (n = 12)

615 ± 110

3.04 ± 0.32

1.87a ± 0.20

14.9b ± 1.9

4.9a ± 0.3

9.16b ± 0.88

4.56b ± 0.70

1.50 ± 0.16

2.80b ± 0.41

NOTE: Values in the table are means ± SE for number of patients indicated in parentheses.

a Significant difference from value for normal pregnancy (p < 0.05).

b Significant difference from value for normal pregnancy (p < 0.01).

SOURCE: Modified from Diamant et al., 1982. This information was published in the American Journal of Obstetrics and Gynecology, Vol 144, Diamant Y. Z., B. E. Metzger, N. Freinkel and E. Shafrir, Placental lipid and glycogen content in human and experimental diabetes mellitus, Pages 5-11, Copyright Elsevier (1982).



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