Outcomes description:

  • Maternal weight gain

  • Preterm delivery


Women with low rate of weight gain (< 0.27 kg/wk) had a 60% higher risk for spontaneous preterm birth compared with those with average weight gain (0.27-0.52 kg/wk). They were also more than twice as likely to deliver preterm as women with a high rate of gain (> 0.52 kg/wk) (OR = 2.54; 95% CI 1.49, 4.88).

Maternal confounders/effect modifiers:

  • Dietary intake

  • Use of cigarettes, alcohol, and illicit drugs

  • Pre-pregnancy weight/height

  • Age

  • Income

  • Marital status

  • Race

  • Use of vitamin supplements

  • Whether or not pregnancy was planned

Infant and child confounders/effect modifiers:


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