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Acronyms ACS American Cancer Society ASCO American Society of Clinical Oncology ASP average sales price ATC4 anatomical therapeutic classification AWP average wholesale price CCDR Canadian Coordinated Drug Review CED coverage with evidence development CMS Centers for Medicare and Medicaid Services FDA U.S. Food and Drug Administration GDP gross domestic product HTA health technology assessment ICD implantable cardiac defibrillator ICER incremental cost-effectiveness ratio IND investigational new drug IOM Institute of Medicine 117
118 assessing and improving value in cancer care NCCN National Comprehensive Cancer Network NCI National Cancer Institute NCPF National Cancer Policy Forum NHS National Health Service (United Kingdom) NICE U.K. National Institute for Health and Clinical Excellence NIH National Institutes of Health NSCLC non-small cell lung cancer PBM pharmacy benefit manager PhRMA Pharmaceutical Research and Manufacturers of America QALY quality-adjusted life-year RCT randomized controlled trial RVU relative value unit VBID value-based insurance design