Ting et al. (2000) found that a DNA sequence just 1,100 bp away from the hybrid sterility gene Odysseus (Ody) was not divergent between the 2 parental species, and from this single observation they concluded that the hitchhiking region around Ody must be extremely small. Wood et al. (2008) and Smadja et al. (2008) extend this idea by suggesting that the nearest genomic region of low genetic divergence to an Fst outlier marks the boundary of its hitchhiking region (Fig. 1.5B).
Several observations are inconsistent with this hypothesis. First, outliers are easy to find. Even in studies with just a few markers (Wilding et al., 2001; Emelianov et al., 2004; Rogers and Bernatchez, 2007; Via and West, 2008), 5% or more of tested markers are generally Fst outliers. Taking 5% as a minimal estimate, this observation implies either that hitchhiking