1. Develop a set of principles and questions to be addressed in developing a framework to guide programs that provide and oversee laboratory security and personnel reliability systems for BSAT research. This framework should optimize benefits, minimize risk, and facilitate the productivity of research.

  2. Review and assess the efficacy and cost/benefit of similar laboratory security, personnel reliability, and BSAT accountability programs of federal agencies to explore best practices across the federal government. The review should consider the implementation of existing legislation, regulations, guidance, policies, and practices as they relate to both federal laboratories or programs and research facilities at representative extramural laboratories funded by government programs.

    The assessment will include potential impacts on the ability to attract and sustain quality scientists to conduct research on BSAT and identification of factors responsible for barriers to research on BSAT in the extramural environment.

    The committee will make recommendations for refining existing programs and procedures affecting both intramural and extramural facilities that will achieve greater productivity in research objectives, optimize management to reduce risk, and produce improved uniformity, transparency, and efficiency in research on BSAT.

  3. Make recommendations to inform policy decisions for achieving an effective system for oversight to ensure compliance with these programs and procedures.

The committee may consider examples of facility security and personnel assurance programs in other settings, including those from outside the BSAT domain and those outside the federal government, that might offer lessons or best practices.

The committee’s conclusions and recommendations were developed independent of the other reports on these topics including those identified above, although the committee did have access to those reports that had been released while the committee was engaged in its work (AAAS 2008, 2009; DHB 2009; DSB 2009; NSABB 2009). The committee did not have access to the reports from the EO Working Group or the Trans-Federal Task Force, which had not been released before the completion of this report.


After the brief introduction to the issues addressed in the report in this chapter, Chapter 2 contains basic factual material describing the current regulatory environment including the development and operation of current U.S. policies to govern BSAT research, a review of other federal regulations related to BSAT research, and a brief discussion of how BSAT research is regulated in other countries. Chapter 3 sets out some basic principles that guided the

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