Finally, speakers and participants proposed that the reimbursement system needs to be adjusted to reward the development and use of high-quality predictive tests. The current reimbursement system of coding, bundling of payments, and using a fixed-fee schedule for predictive tests discourages test innovation; does not adequately recognize the clinical importance of predictive tests; and is not value based. An IOM committee will examine these issues further, and develop consensus-based recommendations for moving the field of personalized medicine forward.