FDA Food and Drug Administration

FISH fluorescent in situ hybridization

FLT3 FMS-like tyrosine kinase 3

GAPPNet Genomic Applications in Practice and Prevention Network

HER2 human epidermal growth factor receptor 2

HHS U.S. Department of Health and Human Services

HRSA Health Resources and Services Administration

IOM Institute of Medicine

IVDMIA In Vitro Diagnostic Multivariate Index Assay

KRAS v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog

MEDCAC Medicare Evidence Development and Coverage Advisory Committee

NCI National Cancer Institute

NIH National Institutes of Health

NLA national limitation amount

OIVD Office of In Vitro Diagnostic Devices

PCR polymerase chain reaction

PET positron emission tomography

PFS progression-free survival

PMA premarket application

PSA prostate-specific antigen

SACGHS Secretary’s Advisory Committee on Genetics, Health, and Society

SACGT Secretary’s Advisory Committee on Genetic Testing

UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1

USPSTF U.S. Preventive Services Task Force



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