Vaccination of adults

Persons at risk for infection by sexual exposure

• Sex partners of HbsAg-positive persons.

• Sexually active persons who are not in a long-term, mutually monogamous relationship (for example, persons with more than one sex partner during the previous 6 months).

• Persons seeking evaluation or treatment for a sexually transmitted disease.

• Men who have sex with men.

Persons at risk for infection by percutaneous or mucosal exposure to blood

• Current or recent injection-drug users.

• Household contacts of HBsAg-positive persons.

• Residents and staff of facilities for developmentally disabled persons.

• Health-care and public-safety workers who have a reasonably anticipated risk of exposure to blood or blood-contaminated body fluids.

• Persons with end-stage renal disease, including predialysis, hemodialysis, peritoneal-dialysis, and home-dialysis patients.

• Incarcerated persons.

Others

• International travelers to regions that have high or intermediate levels (HBsAg prevalence of at least 2%) of endemic HBV infection.

• Persons who have chronic liver disease.

• Persons who have HIV infection.

• All other persons who are seeking protection from HBV infection.

Abbreviations: ACIP, Advisory Committee on Immunization Practices; HBsAg, hepatitis B surface antigen; HBIG, hepatitis B immune globulin.

SOURCE: Adapted from Mast et al., 2005, 2006.