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The Domestic and International Impacts of the 2009-H1N1 Influenza A Pandemic: Global Challenges, Global Solutions: Workshop Summary (2010)
Board on Global Health (BGH)

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. "A13 Influenza (H1N1) Pandemic 2009." The Domestic and International Impacts of the 2009-H1N1 Influenza A Pandemic: Global Challenges, Global Solutions: Workshop Summary. Washington, DC: The National Academies Press, 2010.

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The Domestic and International Impacts of the 2009-H1N1 Influenza a Pandemic: Global Challenges, Global Solutions - Workshop Summary

Virological Surveillance

The virological diagnosis performed well with the surveillance methods more specific to the 2009-H1N1 influenza A virus. It should be noted that diagnosis was first performed at the Institute Malbran, after which another 18 laboratories were enabled to perform real-time (RT)-PCR, three of which are the National Influenza Center of the WHO, which also performed culture and serology for this virus. The percentage of positivity for the new virus was 43.3 percent (8,851/20,409). In the weekly distribution, the circulation of respiratory syncytial virus (RSV) is seen during the whole period but the peak of diagnosis occurred in weeks 25 and 26 for the new virus (Figure A13-9).

Figure A13-10 illustrates that RSV is dominant for children up to age one; however, the 2009-H1N1 influenza A virus was dominant for all other age groups.

Analysis of Severe Acute Respiratory Infections and Death

The age distribution of cases of SARI showed that the largest group affected were the 0- to 4-year-olds, but we must consider that some of these correspond to cases of RSV observed in the laboratory diagnosis. The hospitalization rate was 23.4 per 100,000 inhabitants (Figure A13-11).

The time distribution for hospitalized patients shows a peak in late June, about a week after the peak of the ILI epidemic curve, and the beginning of severe cases shifted by 15 days for ILI during the period in which cases were given treatment and prophylaxis was given to their contacts. As of early July, the intensity

FIGURE A13-9 Distribution of respiratory viruses by epidemiological week, Argentina 2009.

FIGURE A13-9 Distribution of respiratory viruses by epidemiological week, Argentina 2009.

SOURCE: Ministry of Health National Surveillance System.

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Front Matter (R1-R22)
Workshop Overview (1-94)
Appendix A1 Technical Report for State and Local Public Health Officials and School Administrators on CDC Guidance for School (K-12) Responses to Influenza during the 2009-2010 School Year (95-110)
A2 Predicting Emerging Diseases in the Twenty-first Century: The Case of Zoonotic Influenza (111-119)
A3 The Spring 2009 Influenza A H1N1 Outbreak: A Local Public Health Perspective (120-136)
A4 I nternational Law and Equitable Access to Vaccines and Antivirals in the Context of 2009-H1N1 Influenza (137-154)
A5 In Vitro and In Vivo Characterization of New Swine-Origin H1N1 Influenza Viruses (155-190)
A6 Estimation of the Reproductive Number and the Serial Interval in Early Phase of the 2009 Influenza A⁄H1N1 Pandemic in the USA (191-207)
A7 The Severity of Pandemic H1N1 Influenza in the United States, from April to July 2009: A Bayesian Analysis (208-247)
A8 Hard Choices in Difficult Situations: Ethical Issues in Public Health Emergencies (248-268)
A9 Rumors of Pandemic: Monitoring Emerging Disease Outbreaks on the Internet (269-282)
A10 Preliminary Observation of the Epidemiology of Seasonal and Pandemic Influenza A (H1N1) in South Africa, 2009 (283-296)
A11 Reflections on the 1976 Swine Flu Vaccination Program (297-305)
A12 Southern Hemisphere, Northern Hemisphere: A Global Influenza World (306-326)
A13 Influenza (H1N1) Pandemic 2009 (327-341)
A14 Origins and Evolutionary Genomics of the 2009 Swine-Origin H1N1 Influenza A Epidemic (342-380)
Appendix B Agenda (381-385)
Appendix C Acronyms (386-388)
Appendix D Glossary (389-396)
Appendix E Forum Member Biographies (397-418)