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Research at the Intersection of the Physical and Life Sciences
ecosystems in great detail. It is obvious, however, that new techniques must be developed to study interactions at small and large scales. The top-down approach to instrument design and technique development will continue to be important for research; indeed, for some systems and size scales, it will likely be the only path available. On the molecular level, however, bottom-up technologies promise to make the direct study and control of subcellular interactions possible.
Bertozzi, C.R., and L.L. Kiessling, 2001. Chemical glycobiology, Science 291: 2357.
Biel, S., 2006. Adenoviridae: Human adenovirus C. ICTVdB Management 00.001.0.01.001. Human adenovirus C. In ICTVdB —The Universal Virus Database, version 4. C. Büchen-Osmond, ed. New York, N.Y.: Columbia University.
Gibson, E. A., A. Paul, N. Wagner, R. Tobey, D. Gaudiosi, S. Backus, I. Christov, A. Aquila, E.M. Gullikson, D.T. Attwood, M.M. Murnane, and H.C. Kapteyn, 2003. Coherent soft x-ray generation in the water window with quasi-phase matching, Science 302: 95.
Ilic, B., H.G. Craighead, S. Krylov, W. Senaratne, C. Ober, and P. Neuzil, 2004. Attogram detection using nano-electromechanical oscillators, Journal of Applied Physics 95: 33694-3703.
Marko, J.F., 2008. Micromechanical studies of mitotic chromosomes, Chromosome Research 16: 469.
Marvin, D.A., L.C. Welsh, M.F. Symmons, W.R.P. Scott, and S.K. Straus, 2006. Molecular structure of fd (f1, M13) filamentous bacteriophage refined with respect to x-ray fibre diffraction and solid-state NMR data supports specific models of phage assembly at the bacterial membrane, Journal of Molecular Biology 355, 294-309.
Minton, A.P., 2006. How can biochemical reactions within cells differ from those in test tubes? Journal of CellScience 119: 2863.
Motter, A.E., N. Gulbahce, N. Almaas, and A.L. Barabasi, 2008. Predicting synthetic rescues in metabolic networks, Molecular Systems Biology 4: 168.
National Research Council, 2009. A New Biology for the 21st Century. Washington, D.C.: The National Academies Press.
Newman, M., 2008. The physics of networks, Physics Today 61: 33.
Rivas, G., F. Ferrone, and J. Herzfeld, 2004. Life in a crowded world, EMBO Reports 5: 23.
Sayre, D., 1980. Imaging Processes and Coherence in Physics. Springer Lecture Notes in Physics, Vol. 112, M. Schlenker et al., eds. Berlin: Springer Vertag pp. 229-235.
Sega, M., P. Faccioli, F. Pederiva, G. Garberoglio, and H. Orland, 2007. Quantitative protein dynamics from dominant folding pathways, Physical Review Letters 99: 118102.
Tsuyama, N., H. Mizuno, E. Tokunaga, and T. Masujima, 2008. Live single-cell molecular analysis by video-mass spectrometry, Analytical Sciences 24: 559.
Vernizzi, G., and M.O. de la Cruz, 2007. Faceting ionic shells into icosahedra via electrostatics, Proceedings of theNational Academy of Sciences 104: 18382.
Vernizzi, G., K.L. Kohlstedt, and M.O. de la Cruz, 2009. The electrostatic origin of chiral patterns on nanofibers, Soft Matter 5: 736.
Whitesides, G. M., and B. Grzybowski, 2002. Self-assembly at all scales, Science 295: 2418.
Yu, J., J. Xiao, X.J. Ren, K.Q. Lao, and X.S. Xie, 2006. Probing gene expression in live cells, one protein molecule at a time, Science 311: 1600.
Zhang, C., M. Su, Y. He, X. Zhao, P. Fang, A.E. Ribbe, W. Jiang, and C. Mao, 2008. Conformational flexibility facilitates self-assembly of complex DNA nanostructures, Proceedings of the National Academy of Sciences ofthe United States of America 105: 10665.
Zhang, X., C. Sun, and N. Fang, 2004. Manufacturing at nanoscale: Top-down, bottom-up and system engineering, Journal of Nanoparticle Research 6:125.