Study

Design

Population

Outcomes

Results

Adjustments

Comments

 

 

 

 

FVC, but not FEV1, associated with self-report of oil-fire exposure

 

use of modeled oil-fire exposures

Ishoy et al., 1999b (Vol. 4)

Cross-sectional, population-based, medical evaluation

686 peace-keeping Danish deployed to Gulf War theater vs 231 nondeployed controls

Shortness of breath; FVC; FEV1; peak flow

14% vs 3.5% Percent of predicted:

100.7 vs 100.7, NS

95.6 vs 96.4, NS

94.0 vs 92.8, NS

None

Appropriate population-based controls but differential participation: 84% deployed vs 58% nondeployed; smoking histories similar in deployed and nondeployed

Smith et al., 2006 (Update)

Hospitalizations cohort study (cohort data from DMDC)

Active-duty personnel with a single deployment to: Gulf War theater (n = 455,465); Southwest Asia peacekeeping mission, 1991-1998 (n = 249,047); Bosnia, 1995-1998 (n = 44,341)

Postdeployment hospitalization events (1991-2000) for an ICD-9-CM diagnosis of respiratory disease (140-208), and for testicular cancer specifically

Veterans of Bosnia compared to GWV: HR 0.73 (95% CI 0.63-0.84)

Veterans of Southwest Asia compared to GWV: HR 1.08 (95% CI 1.00-1.16)

Sex, age, marital status, pay grade, race/ethnicity, service branch, occupation, and predeployment hospitalization; time-dependent covariate to account for changing hospitalization methods, diagnostic criteria, and procedures

Active-duty personnel only; hospitalizations at DoD facilities only

Macfarlane et al., 2000, 2005 (Update)

Cohort study

2000: 53,462 UK GWVs vs 53,450 nondeployed UK veterans 2005: 51,753 UK GWVs and 50,808 nondeployed UK veterans

Mortality (1991-1999/2004) due to diseases of the respiratory system

2000: 3 deaths in GWVs compared to 3 deaths in control group, MRR 1.0 (95% CI 0.1-7.5)

2005: 9 deaths in GWVs compared to 6 deaths in control group, MRR 1.64 (95% CI 0.58-4.66)

Matching by sex, age, branch, fitness for service

 



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