Canadian Gulf War Veterans Study, 44, 58

derivative studies, 44, 58

diseases of the digestive system, 158, 166

mental and behavioral disorders, 105

chronic fatigue syndrome, 213

reference study, 44, 58

Cancer

all cancers, 8, 74-75, 80-82, 257

brain cancer, 2, 9, 10, 20, 73-74, 75, 76, 78, 79, 125, 231, 261

conclusions, 8, 78, 257

deployment status and, 74-80

derivative studies, 42, 44, 52

digestive tract, 76

hospitalization studies, 73, 74, 75-76, 80, 81

incidence, 42, 52, 57, 78

latency, 8, 28, 41, 73, 74, 78

leukemias and lymphomas, 73

mortality studies, 73, 74-75, 76, 78, 79, 80, 81, 82, 125, 226-227

nerve agent exposure and, 73-74, 75, 77, 78, 79

oil-well fire smoke and, 74, 75, 78

pesticide exposure and, 78

prevalence, 76, 77

primary studies, 75-76, 79-82, 125

recommendation, 78

registry data, 9

research recommendations, 9, 10

secondary studies, 76-78

skin, 73, 76, 77, 78, 166

testicular, 2, 4, 15, 19, 73, 74, 76, 78, 79-80, 81, 208

updated and supplemental literature, 75-78

vaccines/vaccination and, 77

Volume 4 summary, 4, 19, 20, 73-75

Carbamates, 266, 267, 268

Cardiac dysrhythmia, 135, 140, 141

Cardiovascular disease. See Circulatory system diseases

Cause-specific mortality. See External causes of mortality

Centers for Disease Control and Prevention (CDC), 47, 49, 52, 59, 116, 200, 205, 208, 210, 211, 212, 213, 219, 220, 256, 270

Central nervous system (CNS), 160, 267, 270, 275, 276, 278, 279

Chalder Fatigue Scale, 213

Chemical agent exposure, and neurological diseases, 47, 59-60, 121, 133

Chemical and biologic warfare

exposure to agents of, 49, 58

threat of, 14-15, 55, 212, 213

Chlorinated hydrocarbons, 14

Cholinesterase inhibitors.

See also Pesticide/insecticide

exposures;

Pyridostigmine bromide

animal studies, 275-276

exposures during Gulf War, 266-270

genetic susceptibility, 61, 276-278

illnesses associated with, 60, 267-268

long-term effects of low doses, 270

multisymptom illnesses, 57, 61, 62, 278-279

studies in Gulf War populations, 60, 271-274

Chronic dysphoria, 105

Chronic fatigue syndrome (CFS), 7.

See also Multisymptom illnesses

chemical sensitivity and, 45

comorbidities, 157, 163

conclusions, 8, 214, 256

definition, 210-211, 212

diagnosis, 41, 211

in disabled veterans, 52, 214, 220

etiology, 121, 211

identification of predictors, 42

mental and behavioral disorders and, 102

multisymptom illnesses, 60, 207, 211

oil-fire smoke exposure and, 214

pesticide exposure and, 52, 55, 213, 214

prevalence, 46, 47, 53, 55, 60, 61, 213, 214

primary studies, 211-212, 219-220

pyridostigmine bromide and, 55, 213, 214

secondary studies, 212-213

threat of chemical weapons and, 55, 212, 213

updated and supplemental literature, 213-214, 220

Volume 4 summary, 19, 211-213

war stress and, 102, 213

Chronic multisymptom illness (CMI). See Multisymptom illnesses

Chronic obstructive pulmonary disease, 145, 148, 150

Chronic widespread pain (CWP).

See also Fibromyalgia

alcohol use and, 177

cognitive performance, 50, 118

combat exposure and, 50, 177, 178

comorbid with mental disorders, 102

conclusions, 8, 257

delayed-onset, 177

identification of predictors of, 42, 50

pesticide exposure and, 178

pyridostigmine bromide exposure and, 178

musculoskeletal, 1, 3, 10, 18, 19, 47, 57, 118, 120

prevalence, 53, 177

primary studies, 176-177, 178, 179

secondary studies, 177-178

self-reports of, 18, 42, 43, 57

stress perceptions and, 177, 178

Volume 4 summary, 3

Circulatory system diseases.

See also specific diseases and conditions

birth defects, 189, 200

conclusions, 8, 140, 257

female veterans, 138

hospitalization studies, 135, 136, 137, 140, 141, 142, 218

latency, 28



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