Macfarlane et al., 2005 (Update)

Mortality cohort; 13-year follow-up

51,753 UK GW deployed veterans and 50,808 era veterans, randomly selected, matched by age, sex, service branch, rank; also fitness for active service in the army and Royal Air Force

Mortality due to malignant neoplasms

GWVs (123 deaths) compared to era veterans (130 deaths):

MRR 1.01 (95% CI 0.79-1.30)


Complete and long-term follow-up; cohort of moderate size; potentially other uncontrolled confounders such as smoking

NOTE: BIRLS = Beneficiary Identification Records Locator System; CCD = Canadian Cancer Database; CMD = Canadian Mortality Database; DMDC = Defense Manpower Data Center; GW = Gulf War; GWV = Gulf War veteran; HR = adjusted hazard ratio; MMR = mortality rate ratio; NDI = National Death Index; NDV = nondeployed veteran; NHSCR = National Health Service Central Register; PHQ = Patient Health Questionnaire; PIR = proportional incidence ratio; RR = adjusted risk ratio; SEER = Surveillance Epidemiology and End Results; SF-12 = 12-item short form health survey; SIR = standardized incidence ratio; SMR = standardized mortality ratio; SRR = standardized rate ratio.

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