ers and related equipment) to fulfill this responsibility. Detailed information on the role and function of the IACUC is provided later in this chapter.


Interinstitutional collaboration has the potential to create ambiguities about responsibility for animal care and use. In cases of such collaboration involving animal use (beyond animal transport), the participating institutions should have a formal written understanding (e.g., a contract, memorandum of understanding, or agreement) that addresses the responsibility for offsite animal care and use, animal ownership, and IACUC review and oversight (AAALAC 2003). In addition, IACUCs from the participating institutions may choose to review protocols for the work being conducted.

Personnel Management

Training and Education

All personnel involved with the care and use of animals must be adequately educated, trained, and/or qualified in basic principles of laboratory animal science to help ensure high-quality science and animal well-being. The number and qualifications of personnel required to conduct and support a Program depend on several factors, including the type and size of the institution, the administrative structure for providing adequate animal care, the characteristics of the physical plant, the number and species of animals maintained, and the nature of the research, testing, teaching, and production activities. Institutions are responsible for providing appropriate resources to support personnel training (Anderson 2007), and the IACUC is responsible for providing oversight and for evaluating the effectiveness of the training program (Foshay and Tinkey 2007). All Program personnel training should be documented.

Veterinary and Other Professional Staff Veterinarians providing clinical and/or Program oversight and support must have the experience, training, and expertise necessary to appropriately evaluate the health and wellbeing of the species used in the context of the animal use at the institution. Veterinarians providing broad Program direction should be trained or have relevant experience in laboratory animal facility administration and management. Depending on the scope of the Program, professionals with expertise in other specific areas may be needed—in, for example, facility design and renovation, human resource management, pathology of laboratory animals, comparative genomics, facility and equipment maintenance, diagnostic laboratory operations, and behavioral management. Laboratory

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