Ceilings, 56, 81, 142

Centers for Disease Control and Prevention, 19, 21, 107, 148, 157

Cercopithecine herpesvirus 1, 23

Chairing, 29

Chemical agents

cleaning materials, 71, 72

non-pharmaceutical-grade, 31

hazardous, 18, 19, 20, 21, 136

Chickens, 48, 60

Chimpanzees, xviii, 61

Chlorines and chloramines, 72, 78-79, 80, 85, 86

Circadian rhythm, 43, 48, 49, 137, 149

Cleaning agents, 18, 71, 72

(see also Sanitation)

(see also Vetterinary care)

Clinical care and management

emergency care, 114

medical management, 114

recordkeeping, 115

Clothing and footwear, 20, 21, 146

Cold storage and refrigeration, 66, 73, 136, 142

Cold stress, 43, 44, 53

Collaborations, interinstitutional, 15

Computer modeling

alternative to animal use, 5, 12, 25, 199

facility design, 46, 133

genetic variability, 76

Conditioned-response protocols, 31

Construction guidelines, 136-143

Containment of hazardous materials, 21, 148-149

Contaminants

airborne, 22, 45, 46-47, 139, 140, 143, 145, 146-147, 149

bedding, 69, 141, 146

cleaning implements, 72, 85

food, 19, 65, 66, 67, 84, 141, 146

genetic, 76

microbial, 72, 81, 108, 109, 110, 113, 118, 144-145

recommended readings

water, 67-68, 81, 86, 138

Convention on International Trade in Endangered Species of Wild Fauna and Flora, 107

Corridors, 86, 134, 136, 137, 141, 142

Cryogens, 147

Cryopreservation, 76, 107

Cyanobacteria, 86

D

Defecation, 72

Definitions

animal biosecurity, 109

animal care and use program, 6, 11

animal use, 2

attending veterinarian, 14

engineering standard, 6

humane care, 6

institutional animal care and use committee, 14

institutional official, 13

laboratory animals, 2

life support system, 79

macroenvironment, 42

“may,” 8

microenvironment, 42

“must,” 8

performance standard, 6-7

policies, 7

practice standard, 7

principles, 7

procedures, 7

“should,” 8

thermoneutral zone, 43

three Rs, 4-5

Dehydration, 68

Desiccation stress, 45, 46

Diet and dietary control

(see also Food and feedng)

abrupt changes in, 67

aquatic animals, 84, 85

autoclavable, 66

caloric management, 31, 57, 67

certified diets, 65

chemically defined diets, 65, 66

natural-ingredient, 65, 66

nutritionally balanced, 67

purified diets, 65, 66

quality assurance, 65, 66

treats, 67

Disaster planning, 35, 74-75

Disease control, 23, 72, 81, 108, 109, 110, 112-113, 118, 144-145, 190

Disease susceptibility, 19, 42



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