. "Appendix C: National Academies' Guidelines for Human Embryonic Stem Cell Research, Amended as of May 2010." Final Report of The National Academies' Human Embryonic Stem Cell Research Advisory Committee and 2010 Amendments to The National Academies' Guidelines for Human Embryonic Stem Cell Research. Washington, DC: The National Academies Press, 2010.
The following HTML text is provided to enhance online
readability. Many aspects of typography translate only awkwardly to HTML.
Please use the page image
as the authoritative form to ensure accuracy.
Final Report of the National Academies’ Human Embryonic Stem Cell Research Advisory Committee and 2010 Amendments to the National Academies’ Guidelines for Human Embryonic Stem Cell Research
for the use of the scientific community, including researchers in university, industry, or other private-sector research organizations who are conductingsuch research with non-federal funding.Researchers conducting federally-funded hES cell research should, however, note that the requirements of theNational Institutes of Health (NIH)—available athttp://stemcells.nih.gov/policy/2009guidelines.htm—supersedethese National Academies’ Guidelines for certain sections (as noted below).
1.1 What These Guidelines Cover
1.1(a) These guidelines cover all derivation of hES cell lines and all research that uses hES cells derived from
blastocysts and/or morulae made for reproductive purposes and later obtained for research from in vitro fertilization (IVF) clinics,
blastocysts and/or morulae made specifically for research using IVF,
somatic cell nuclear transfer (NT) into oocytes or by parthenogensis or androgenesis.
1.1(b) Some of the concerns addressed in this report are common to other types of human stem cell research; as such, certain of these Guidelines should also apply to those other types of research. For example,
research that uses human adult stem cells,
research that uses fetal stem cells or embryonic germ cells derived from fetal tissue; such research is covered by federal statutory restrictions at 42 U.S.C. 289g-2(a) and federal regulations at 45 CFR 46.210,
research using hPS cells derived from non-embryonic sources, such as spermatogonial stem cells and “induced pluripotent” stem cells derived from somatic cells by introduction of genes or otherwise (so-called iPS cells), as well as other pluripotent cells yet to be developed; guidelinesfor hPS cells are collected inSection 7below.
Recommendations as to which guidelines apply to other hPS cells are collected in a new Section 7 below. Institutions and investigators conducting research with adult and fetal stem cells should also consider which individual provisions of these guidelines are relevant to their research.