The following types of research should not be conducted at this time:
Research involving in vitro culture of any intact human embryo, regardless of derivation method, for longer than 14 days or until formation of the primitive streak begins, whichever occurs first.
Research in which hES cells are introduced into nonhuman primate blastocysts or in which any embryonic stem cells are introduced into human blastocysts.
No animal into which hES cells have been introduced such that they could contribute to the germ line should be allowed to breed.
All scientific investigators and their institutions, regardless of their field, bear the ultimate responsibility for ensuring that they conduct themselves in accordance with professional standards and with integrity. In particular, people whose research involves hES cells should work closely with oversight bodies, demonstrate respect for the autonomy and privacy of those who donate gametes, morulae, blastocysts, or somatic cells and be sensitive to public concerns about research that involves human embryos.
1.5(a) It is acceptable to use hES cell lines that were approved in August 2001 for use in U.S. federally funded research. 1.5(b) ESCRO committees should include on their registry a list of NIH-approved cell lines that have been used at their institution in accord with the requirement in section 2.0 of the Guidelines. 1.5(c) Presence on the list of NIH-approved cell lines constitutes adequate documentation of provenance, as per Section 6.1 of the Guidelines.