tissues retain identifiers linked to living individuals, human subjects protections may apply.
3.7 Clinical personnel who have a conscientious objection to hES cell research should not be required to participate in providing donor information or securing donor consent for research use of gametes, morulae, or blastocysts. That privilege should not extend to the care of a donor or recipient.
3.8 Researchers may not ask members of the infertility treatment team to generate more oocytes than necessary for the optimal chance of reproductive success. An infertility clinic or other third party responsible for obtaining consent or collecting materials should not be able to pay for or be paid for the material obtained (except for specifically defined cost-based reimbursements and payments for professional services).
4.1 Requests to the ESCRO committee for permission to attempt derivation of new hES cell lines from donated embryos, morulae, or blastocysts must include evidence of IRB approval of the procurement process (see Section 3.0 above).
4.2 The scientific rationale for the need to generate new hES cell lines, by whatever means, must be clearly presented, and the basis for the numbers of embryos, morulae, and blastocysts needed should be justified.
4.3 Research teams should demonstrate appropriate expertise or training in derivation or culture of either human or nonhuman ES cells before permission to derive new lines is given.
4.4 When NT experiments involving either human or nonhuman oocytes are proposed as a route to generation of hES cells, the protocol must have a strong scientific rationale. Proposals that include studies to find alternatives to donated oocytes in this research should be encouraged.
4.5 Neither blastocysts or morulae made using NT of human nuclei (whether produced with human or nonhuman oocytes) nor parthenogenetic or androgenetic human embryos may be transferred to a human or nonhuman uterus or cultured as intact embryos in vitro for longer than 14 days or until formation of the primitive streak, whichever occurs first.