Appendix B
Agenda

Antimicrobial Resistance: Implications for Global Health and Novel Intervention Strategies


April 6–7, 2010

Keck Building, Room 100

500 Fifth Street, NW

Washington, DC


DAY 1: APRIL 6, 2010

8:30–9:00:

Registration and Continental Breakfast

9:00–9:15:

Welcoming Remarks: David A. Relman, M.D., Chair, and James M. Hughes, M.D., Vice-Chair, Forum on Microbial Threats

9:15–10:00:

Keynote Remarks: The Effects of Antibiotic and Pesticide Resistance on Public Health

 

David Pimentel, Ph.D.

Cornell University

10:00–10:30:

Discussion

10:30–10:45:

Break

Session I
Where Does Resistance Come From?

Moderator: David A. Relman, M.D.

10:45–11:15:

Origins of AMR—Antimicrobials as Agents of Selection and Directed Evolution

 

Henry Chambers, M.D.

University of California, San Francisco



The National Academies | 500 Fifth St. N.W. | Washington, D.C. 20001
Copyright © National Academy of Sciences. All rights reserved.
Terms of Use and Privacy Statement



Below are the first 10 and last 10 pages of uncorrected machine-read text (when available) of this chapter, followed by the top 30 algorithmically extracted key phrases from the chapter as a whole.
Intended to provide our own search engines and external engines with highly rich, chapter-representative searchable text on the opening pages of each chapter. Because it is UNCORRECTED material, please consider the following text as a useful but insufficient proxy for the authoritative book pages.

Do not use for reproduction, copying, pasting, or reading; exclusively for search engines.

OCR for page 420
Appendix B Agenda Antimicrobial Resistance: Implications for Global Health and Novel Intervention Strategies April 6–7, 2010 Keck Building, Room 100 500 Fifth Street, NW Washington, DC DAy 1: APRIL 6, 2010 8:30–9:00: Registration and Continental Breakfast 9:00–9:15: Welcoming Remarks: David A. Relman, M.D., Chair, and James M. Hughes, M.D., Vice-Chair, Forum on Microbial Threats 9:15–10:00: Keynote Remarks: The Effects of Antibiotic and Pesticide Resistance on Public Health David Pimentel, Ph.D. Cornell University 10:00–10:30: Discussion 10:30–10:45: Break Session I Where Does Resistance Come From? Moderator: David A. Relman, M.D. 10:45–11:15: Origins of AMR—Antimicrobials as Agents of Selection and Directed Evolution Henry Chambers, M.D. University of California, San Francisco 0

OCR for page 420
 APPENDIX B 11:15–11:45: Population Mobility, Globalization, and AMR Douglas MacPherson, M.D., M.Sc. (CTM), FRCPC Migration Health Consultants, Inc., and McMaster University 11:45–12:15: Antibiotics in the Environment: Natural and Anthropogenic Contributions Julian Davies, Ph.D. University of British Columbia 12:15–12:45: Discussion of Session I 12:45–1:30: Lunch Session II Antimicrobial Resistance: Evolution/Ecology/Environment Moderators: Frederick Sparling, M.D., and Lonnie King, D.V.M. 1:30–2:00: AMR in the Environment and the Evolution of Resistance Gerard Wright, Ph.D. McMaster University 2:00–2:30: Antibiotic-Induced Resistance Flow Patrice Courvalin, M.D. Institut Pasteur 2:30–3:00: The Contribution of Antimicrobial Use in Food Animal Production to the Emergence of Antimicrobial Resistance in Human Pathogens Jørgen Schlundt, Ph.D., D.V.M. World Health Organization 3:00–3:30: Questions 3:30–3:45: Break 3:45–4:15: Antimicrobial Resistance in Europe: Burden and Successful Prevention and Control Initiatives Dominique L. Monnet, Pharm.D., Ph.D. European Centre for Disease Prevention and Control (ECDC)

OCR for page 420
 ANTIBIOTIC RESISTANCE 4:15–4:45: Current and Future Trends/Projections in AMR—What Does the Problem Look Like in 5, 10 Years? Ramanan Laxminarayan, Ph.D., M.P.H. Resources for the Future and Princeton University 4:45–5:15: What Is Causing the Antibiotic Pipeline to Dry Up? Brad Spellberg, M.D. University of California, Los Angeles 5:15–5:45: Hospital and Societal Costs of AMR Infections Robert Weinstein, M.D. John Stroger Hospital of Cook County 5:45–6:15: Questions and Discussion DAy 2: APRIL 7, 2010 Paths Forward: Novel Therapeutic Approaches, Mitigation, Intervention 8:15–8:30: Continental Breakfast 8:30–8:45: Summary of Day 1 and Preview of Day 2: David Relman, M.D. Session III Novel Approaches for Drug Discovery, Development, and Mitigation of Resistance Moderator: Jesse Goodman, M.D., M.P.H. 8:45–9:15: Antibiotic Scaffolds: Past, Present, and Future Michael Fischbach, Ph.D. University of California, San Francisco 9:15–9:45: Radical Mechanisms Leading to Antibiotic Resistance James J. Collins, Ph.D. Boston University 9:45–10:15: Novel Approaches for Drug Discovery Kim Lewis, Ph.D. Northeastern University 10:15–10:30: Break

OCR for page 420
 APPENDIX B 10:30–11:00: Returning to Pathogen Specificity with Antibody Therapy Arturo Casadevall, M.D., Ph.D. Albert Einstein College of Medicine 11:00–11:30: Challenges in Antimicrobial Susceptibility Testing of Clinical and Environmental Isolates Fred Tenover, Ph.D., D(ABMM), F(AAM), F(IDSA) Cepheid 11:30–12:00: Clinical Management Issues, Outcomes Louis B. Rice, M.D. Louis Stokes Cleveland VA Medical Center 12:00–12:30: Discussion of Session III 12:30–1:15: Lunch Session IV Think Globally, Act Regionally (and Locally): Panel Discussion on Prudent Use, Stewardship, Global Engagement, Incentives: How Do We Get from Where We Are to Where We Want to Be? Moderators: David Heymann, M.D., and James Hughes, M.D. 1:15–2:15: Prudent Use, Stewardship, Market Incentives, and Global Engagement Stuart Levy, M.D., Tufts University and the Alliance for Prudent Use of Antibiotics Shelley Hearne, Ph.D., The Pew Charitable Trusts Jeffrey Levi, Ph.D., Trust for America’s Health 2:15–4:30: Open Discussion with Panelists, Forum Members, and Audience Julian Davies, Ph.D., University of British Columbia Gerard Wright, Ph.D., McMaster University Jørgen Schlundt, Ph.D., D.V.M., World Health Organization Brad Spellberg, M.D., University of California, Los Angeles Ed Cox, M.D., M.P.H., Food and Drug Administration/Center for Drug Evaluation and Research 4:30–5:00: James Hughes, M.D., and David Relman, M.D., Wrap-Up and Adjournment 5:00: Meeting Adjourns