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Suggested Citation:"Appendix B: Agenda." Institute of Medicine. 2010. Antibiotic Resistance: Implications for Global Health and Novel Intervention Strategies: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/12925.
×

Appendix B
Agenda

Antimicrobial Resistance: Implications for Global Health and Novel Intervention Strategies


April 6–7, 2010

Keck Building, Room 100

500 Fifth Street, NW

Washington, DC


DAY 1: APRIL 6, 2010

8:30–9:00:

Registration and Continental Breakfast

9:00–9:15:

Welcoming Remarks: David A. Relman, M.D., Chair, and James M. Hughes, M.D., Vice-Chair, Forum on Microbial Threats

9:15–10:00:

Keynote Remarks: The Effects of Antibiotic and Pesticide Resistance on Public Health

 

David Pimentel, Ph.D.

Cornell University

10:00–10:30:

Discussion

10:30–10:45:

Break

Session I
Where Does Resistance Come From?

Moderator: David A. Relman, M.D.

10:45–11:15:

Origins of AMR—Antimicrobials as Agents of Selection and Directed Evolution

 

Henry Chambers, M.D.

University of California, San Francisco

Suggested Citation:"Appendix B: Agenda." Institute of Medicine. 2010. Antibiotic Resistance: Implications for Global Health and Novel Intervention Strategies: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/12925.
×

11:15–11:45:

Population Mobility, Globalization, and AMR

 

Douglas MacPherson, M.D., M.Sc. (CTM), FRCPC

Migration Health Consultants, Inc., and McMaster University

11:45–12:15:

Antibiotics in the Environment: Natural and Anthropogenic Contributions

 

Julian Davies, Ph.D.

University of British Columbia

12:15–12:45:

Discussion of Session I

12:45–1:30:

Lunch

Session II
Antimicrobial Resistance: Evolution/Ecology/Environment

Moderators: Frederick Sparling, M.D., and Lonnie King, D.V.M.

1:30–2:00:

AMR in the Environment and the Evolution of Resistance

 

Gerard Wright, Ph.D.

McMaster University

2:00–2:30:

Antibiotic-Induced Resistance Flow

 

Patrice Courvalin, M.D.

Institut Pasteur

2:30–3:00:

The Contribution of Antimicrobial Use in Food Animal Production to the Emergence of Antimicrobial Resistance in Human Pathogens

 

Jørgen Schlundt, Ph.D., D.V.M.

World Health Organization

3:00–3:30:

Questions

3:30–3:45:

Break

3:45–4:15:

Antimicrobial Resistance in Europe: Burden and Successful Prevention and Control Initiatives

 

Dominique L. Monnet, Pharm.D., Ph.D.

European Centre for Disease Prevention and Control (ECDC)

Suggested Citation:"Appendix B: Agenda." Institute of Medicine. 2010. Antibiotic Resistance: Implications for Global Health and Novel Intervention Strategies: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/12925.
×

4:15–4:45:

Current and Future Trends/Projections in AMR—What Does the Problem Look Like in 5, 10 Years?

 

Ramanan Laxminarayan, Ph.D., M.P.H.

Resources for the Future and Princeton University

4:45–5:15:

What Is Causing the Antibiotic Pipeline to Dry Up?

 

Brad Spellberg, M.D.

University of California, Los Angeles

5:15–5:45:

Hospital and Societal Costs of AMR Infections

 

Robert Weinstein, M.D.

John Stroger Hospital of Cook County

5:45–6:15:

Questions and Discussion

DAY 2: APRIL 7, 2010


Paths Forward: Novel Therapeutic Approaches, Mitigation, Intervention

8:15–8:30:

Continental Breakfast

8:30–8:45:

Summary of Day 1 and Preview of Day 2: David Relman, M.D.

Session III
Novel Approaches for Drug Discovery, Development, and Mitigation of Resistance

Moderator: Jesse Goodman, M.D., M.P.H.

8:45–9:15:

Antibiotic Scaffolds: Past, Present, and Future

 

Michael Fischbach, Ph.D.

University of California, San Francisco

9:15–9:45:

Radical Mechanisms Leading to Antibiotic Resistance

 

James J. Collins, Ph.D.

Boston University

9:45–10:15:

Novel Approaches for Drug Discovery

 

Kim Lewis, Ph.D.

Northeastern University

10:15–10:30:

Break

Suggested Citation:"Appendix B: Agenda." Institute of Medicine. 2010. Antibiotic Resistance: Implications for Global Health and Novel Intervention Strategies: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/12925.
×

10:30–11:00:

Returning to Pathogen Specificity with Antibody Therapy

 

Arturo Casadevall, M.D., Ph.D.

Albert Einstein College of Medicine

11:00–11:30:

Challenges in Antimicrobial Susceptibility Testing of Clinical and Environmental Isolates

 

Fred Tenover, Ph.D., D(ABMM), F(AAM), F(IDSA)

Cepheid

11:30–12:00:

Clinical Management Issues, Outcomes

 

Louis B. Rice, M.D.

Louis Stokes Cleveland VA Medical Center

12:00–12:30:

Discussion of Session III

12:30–1:15:

Lunch

Session IV
Think Globally, Act Regionally (and Locally): Panel Discussion on Prudent Use, Stewardship, Global Engagement, Incentives: How Do We Get from Where We Are to Where We Want to Be?

Moderators: David Heymann, M.D., and James Hughes, M.D.

1:15–2:15:

Prudent Use, Stewardship, Market Incentives, and Global Engagement

 

Stuart Levy, M.D., Tufts University and the Alliance for Prudent Use of Antibiotics

 

Shelley Hearne, Ph.D., The Pew Charitable Trusts

 

Jeffrey Levi, Ph.D., Trust for America’s Health

2:15–4:30:

Open Discussion with Panelists, Forum Members, and Audience

 

Julian Davies, Ph.D., University of British Columbia

Gerard Wright, Ph.D., McMaster University

Jørgen Schlundt, Ph.D., D.V.M., World Health Organization

Brad Spellberg, M.D., University of California, Los Angeles

Ed Cox, M.D., M.P.H., Food and Drug Administration/Center for Drug Evaluation and Research

4:30–5:00:

James Hughes, M.D., and David Relman, M.D., Wrap-Up and Adjournment

5:00:

Meeting Adjourns

Suggested Citation:"Appendix B: Agenda." Institute of Medicine. 2010. Antibiotic Resistance: Implications for Global Health and Novel Intervention Strategies: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/12925.
×
Page 420
Suggested Citation:"Appendix B: Agenda." Institute of Medicine. 2010. Antibiotic Resistance: Implications for Global Health and Novel Intervention Strategies: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/12925.
×
Page 421
Suggested Citation:"Appendix B: Agenda." Institute of Medicine. 2010. Antibiotic Resistance: Implications for Global Health and Novel Intervention Strategies: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/12925.
×
Page 422
Suggested Citation:"Appendix B: Agenda." Institute of Medicine. 2010. Antibiotic Resistance: Implications for Global Health and Novel Intervention Strategies: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/12925.
×
Page 423
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Years of using, misusing, and overusing antibiotics and other antimicrobial drugs has led to the emergence of multidrug-resistant 'superbugs.' The IOM's Forum on Microbial Threats held a public workshop April 6-7 to discuss the nature and sources of drug-resistant pathogens, the implications for global health, and the strategies to lessen the current and future impact of these superbugs.

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